CAS: 17877-23-5; Triisopropylsilanol

相似化合物

18173-64-3 18173-88-1 122420-34-2

上下游产品

CAS号6485-79-6 三异丙基硅烷 | CAS号80522-43-6 phenylmethoxy-t... | CAS号33974-42-4 TRIISOPROPYLMET... | CAS号13154-24-0 三异丙基氯硅烷 | CAS号121675-48-7 ethenyl-tri(pro... | CAS号89343-06-6 三异丙基硅基乙炔 | CAS号100-51-6 苯甲醇 | CAS号426-67-5 triisopropylsil... | CAS号17985-17-0 diethoxy-di(pro... | CAS号157859-20-6 丙烯酸三异丙基硅酯 | CAS号13154-24-0 三异丙基氯硅烷

📜三异丙基硅烷置于氧气体系中,用 水,丙酮 用作溶剂,30.0 °C,101.33 Kpa 条件下,反应 1.33H,以99%的收率获得三异丙基硅烷醇
参考文献:O2-Enhanced Catalytic Activity Of Gold Nanoparticles In Selective Oxidation Of Hydrosilanes To Silanols
标题:O2-Enhanced Catalytic Activity Of Gold Nanoparticles In Selective Oxidation Of Hydrosilanes To Silanols
摘要:O2 在氧气氛围下,将氢硅烷氧化成硅醇的过程中,作为金纳米颗粒(aunps)的非消耗性活化剂,提供了相对于氩气氛下反应速率超过200倍的加速效果.在有氧条件下,Aunp 催化剂在氧化反应中表现出高活性,高转换次数(1230000次).包括较不活泼的庞大分子在内的各种氢硅烷,都可以转化为相应的硅醇,并且产率优异.此外,当前的 Aunp 催化剂可以重复使用,同时保持高性能.
Doi:10.1246/cl.150379

专利信息

专利号:US-5442065-A
优先权日:1993-09-09
标 题:Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin
发明人：MAGNUS PHILIP D; ILIADIS THEODORE; EISENBEIS SHANE A; FAIRHURST ROBIN A
权利人:UNIV TEXAS
摘要:A process is described for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin. The synthesis allows efficient production of the enediyne as a stable, compound in good yield from the adamantyl N-protected azabicyclo[7.3.1]tridecadiyne. The adamantyl protecting group is employed in the starting material, N-adamantyl dihydroquinoline or N-adamantyl 6-methoxy quinoline. Also disclosed are process for the synthesis of 3-hydroxy-6-methoxyquinoline and several N-substituted derivatives of azobicyclo[7.3.1]tridecaenediyne. Solid tumor and leukemia assays were performed on the analogs of dynemicin. The results suggest a method that these compounds will useful in treating certain types of leukemias and solid tumors. The disclosed synthesis provides a route to new dynemicin intermediates and analogs which will allow development of second and third generation dynemicins.

专利号:US-8492390-B2
优先权日:2002-05-08
标题 :Synthesis of locked nucleic acid derivatives
发明人：DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER; SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α- L -oxy-LNA, amino-LNA, α- L -amino-LNA, thio-LNA, α- L -thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues.

专利号:EP-1501848-B1
优先权日:2002-05-08
标 题 :Synthesis of locked nucleic acid derivatives
发明人：SORENSEN MADS DETLEF; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as alpha-L-oxy-LNA, amino-LNA, alpha-L-amino-LNA, thio-LNA, alpha-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues. (Formula I)

专利号:US-8759508-B2
优先权日:2007-05-18
标 题 :Chromophoric silyl protecting groups and their use in the chemical synthesis of oligonucleotides
发明人：DELANEY MICHAEL OREN
权利人:DELANEY MICHAEL OREN; GE HEALTHCARE DHARMACON INC
摘要:The compounds are of class of chromophoric 1,2,3-triazolyl equipped silyl linking groups that are useful in the chemical synthesis of RNA. An example of a nucleoside comprising this group is

专利号:US-9403841-B2
优先权日:2012-01-25
标题:Phragamalin limonoids for the treatment of sexual dysfunction
发明人：WIKBERG JARL; JIRGENSONS AIGARS; LIEPINSH EDVARDS
权利人:DICOTYLEDON AB
摘要:The present invention relates to novel chemical compounds, to methods for synthesis of such compounds, and to the use of these novel compounds in the synthesis of other chemical compounds that, inter alia, may be used in the treatment of sexual dysfunction, and for eliciting enhancing effects on sexual behavior. The invention also relates to remarkable biological properties of the novel compounds in their capacity of inducing aggressive behavior.

专利号:US-2013253205-A1
优先权日:2010-09-27
标题 :Process for preparation of aminocyclohexyl ethers and intermediate products used in the process
发明人：GORIN BORIS; DIXON CRAIG EDWARD; OUDENES JAN; BEJAN ELENA VALENTINA; KINSMAN AARON CLEVELAND
权利人:GORIN BORIS; DIXON CRAIG EDWARD; OUDENES JAN; BEJAN ELENA VALENTINA; KINSMAN AARON CLEVELAND; ALPHORA RES INC
摘要:A process for preparation of a compound of formula (I) or or a pharmaceutically acceptable salt, ester, or prodrug thereof, is disclosed. The process involves hydrogenating, in the presence of a catalyst, a compound of formula (II). The different substituents are as described in the specification. Also disclosed are intermediates and processes for their preparation. Further, the process can provide an alternate route for the synthesis of Vernakalant from starting materials that can be readily available.