CAS: 14997-58-1; N-Cbz-L-Histidine

相似化合物

109425-51-6 123333-71-1 135610-90-1

上下游产品

CAS号501-53-1 氯甲酸苄酯 | CAS号71-00-1 L-组氨酸 | CAS号13795-24-9 苄基硝苯基碳酸酯 | CAS号35016-67-2 N,1-Bis[(benzyl... | CAS号59577-41-2 1H-benzo[d][1,2... | CAS号15545-10-5 Z-L-组氨酸甲酯 | CAS号5934-29-2 L-组氨酸盐酸盐,一水 | CAS号645-35-2 L-组氨酸盐酸盐 | CAS号74058-68-7 2-硫酮-3-噻唑烷羧酸苄酯 | CAS号32926-43-5 N-B°C-N'-三苯甲基-L-组氨酸 | CAS号23640-03-1 4-(1H-imidazol-... | CAS号71-00-1 L-组氨酸 | CAS号15545-10-5 Z-L-组氨酸甲酯 | CAS号32675-94-8 2-phenylmethoxy... | CAS号62715-28-0 H-His(Trt)-OMe.HCl

📜L-组氨酸置于氢氧化钾,Sodium Hydroxide,乙醇,水体系中,化学反应生成N-Cbz-L-组氨酸
参考文献:Patchornik Et Al.,Journal Of The American Chemical Society,1957,Vol. 79,P. 6416,6420
标题:Patchornik Et Al.,Journal Of The American Chemical Society,1957,Vol. 79,P. 6416,6420

专利信息

专利号:US-2019177392-A1
优先权日:2014-09-23
标 题 :Synthesis of glp-1 peptides
发明人：PENIAS NAVON SHARON; NAVEH SHIRLY; VASILEIOU ZOI; BARLOS KONSTANTINOS
权利人:NOVETIDE LTD
摘要:Disclosed are processes for the synthesis of GLP-1 peptides, such as liraglutide and semaglutide, and a process for purifying liraglutide.

专利号:US-7435791-B2
优先权日:2001-07-19
标题:Process for rapid solution synthesis of peptides
发明人：EGGEN IVO FRANCI; TEN KORTENAAR PAULUS BERNARDUS; HAASNOOT CORNELIS ALBERT GRUSON
权利人:ORGANON NV
摘要:The present invention relates to a process for rapid solution synthesis of a peptide, the process comprising repetitive cycles of steps (a)-(d):n (a) a coupling step, using an excess of an activated carboxylic component to acylate an amino component, (b) a quenching step in which a scavenger is used to remove residual activated carboxylic functions, wherein the scavenger may also be used for deprotection of the growing peptide, (c) one or more aqueous extractions and optionally, (d) a separate deprotection step, followed by one or more aqueous extractions, characterised in that the process comprises at least one step (b), referred to as step (b′), in which an amine or a thiol comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions. nn During the process of this invention the growing peptide need not be isolated until the final peptide sequence has been obtained. n This highly efficient process is useful for the production of oligo- and polypeptides of high purity.

专利号:US-3953416-A
优先权日:1971-12-20
标 题:Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same
发明人：FOLKERS KARL; CURRIE BRUCE L; CHANG JAW-KANG; SIEVERTSSON HANS; BOGENTOFT CONNY
权利人:FOLKERS KARL; CURRIE BRUCE L; CHANG JAW KANG; SIEVERTSSON HANS; BOGENTOFT CONNY
摘要:A synthetic decapeptide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide which has the hormonal activities of the luteinizing hormone releasing hormone (LRH) of the hypothalamus gland of mammals is produced by utilizing as the key starting materials, the amino acids, glutamic acid or pyroglutamic acid, histidine, tryptophan, serine, tyrosine, glycine, leucine, arginine, and proline. Synthesis of the decapeptide is accomplished by coupling, in appropriate combinations of appropriate protected forms of the amino acids, and finally deprotecting to yield the amide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide.

专利号:BR-PI0202783-B1
优先权日:2001-07-19
标 题:process for the rapid synthesis of a peptide in solution in an organic solvent or a mixture of organic solvents, and methods for the combinatorial synthesis of peptide collections and for automated solution peptide synthesis

专利号:PL-205559-B1
优先权日:2001-07-19
标 题 :Method of peptide synthesis in solution, method of combinatorial synthesis of a peptide library and method of automated peptide synthesis in solution

专利号:US-6416861-B1
优先权日:1999-02-16
标题 :Organosilicon compounds and uses thereof
发明人：LEE YOUNGHEE; SILVERMAN RICHARD B
权利人:UNIV NORTHWESTERN
摘要:A compound of the formula: n and a resin-bound compound of the formula: n and their use in combinatorial chemistry and in the synthesis of compounds comprising at least one aromatic moiety is described, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , P, Ar 1 , and X are as herein defined.