CAS: 1049726-96-6; Sodium 2'-(Dicyclohexylphosphino)-2,6-Dimethoxy-[1,1'-Biphenyl]-3-Sulfonate Hydrate

该化合物是一种复杂的化合物,其独特的结构特征包括一个磺酸盐组,磷酸碱和甲基氧代代二苯基联苯成分.二环己烷基磷酰胺组的存在表明,由于其稳定金属中心的能力,有可能在催化中应用催化作用,特别是在过渡性金属催化反应中.甲基氧基化合物组会增强溶性,并可能影响化合物的电子特性,使之适合各种有机合成应用.作为钠盐,它很可能溶于极地溶剂中,这有利于溶液在溶液阶段反应中使用.氢化物表表明,它在其晶体结构中含有水分子,这可能影响其稳定性和再活性.

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    专利信息


    专利号:US-2023150994-A1
    优先权日:2020-04-07
    标 题:Methods for synthesis of chk1 inhibitors
    发明人:SCHWAEBE MICHAEL; ROSNER THORSTEN; ZHAO DALIAN; MILLER ROSS; DULINA RICH; HUMORA MICHAEL; GOTTSCHLING STEPHEN E
    权利人:SIERRA ONCOLOGY INC
    摘要:The present technology relates to processes, compounds, compositions, and methods useful for coupling reactions. Also, the present disclosure provides for novel intermediates, compositions of matter, and processes relating to the Chk1 inhibitor, SRA737.

    专利号:EP-3567040-B1
    优先权日:2013-06-24
    标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines

    专利号:EP-3567040-A1
    优先权日:2013-06-24
    标题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines

    专利号:EP-4132922-A1
    优先权日:2020-04-07
    标 题 :Methods for synthesis of chk1 inhibitors

    专利号:WO-2025011547-A1
    优先权日:2023-07-10
    标 题 :Method for obtaining on-dna aromatic compound via suzuki coupling reaction and use thereof
    发明人:QU YI; XIA BING; LIN SHUANG; HOU YUXIA; Zhuang Shurong; YANG MINGHUI; ZHANG HAO; GU LIANG; ZHANG PEIYU; MA JIAN
    权利人:JINGTAI ZHIYAO TECH SHANGHAI CO LTD
    摘要:A synthesis method for an On-DNA aromatic compound, comprising subjecting an On-DNA aromatic halide and an organic boric acid, organic borate, organic borate, borane or [Formula 1] to a coupling reaction under the catalysis of a [Pd] catalyst and an alkali, the [Pd] catalyst being a catalyst formed by 2-amino-4,6-dihydroxypyrimidine and divalent palladium. The method is simple, convenient and rapid, and can obtain On-DNA compounds via a Suzuki coupling reaction under a relatively low-temperature condition, thus rapidly expanding the range of application of DNA encoded compound libraries, and adapting to the requirements of large-batch production of DNA encoded compound libraries using multiple-well plates.

    专利号:CN-116411356-A
    优先权日:2021-12-29
    标 题 :Synthesis method of DNA coding compound ribofuranose derivative

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    合成参考文献


    参考文献:10.1007/978-3-319-13054-5_5
    摘要:Traister KM, Molander GA. Improving Transformations Through Organotrifluoroborates. 2015. In: Synthesis and Application of Organoboron Compounds. : Springer International Publishing; 2015.
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