CAS: 7103-09-5; 3-Butenylmagnesium Bromide

上下游产品

1-bromo-4-butene ethylmagnesium bromide magnesium 3-(3-butenyl)cyclopentanone (E)-hepta-6,3-dien-2-one pent-4-enoic acid 1-(5,5-Dimethyl-cyclohexa-1,3-dienyl)-pent-4-en-1-ol

专利信息

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:US-2017081347-A1
优先权日:2014-04-14
标题:Functionalized azaborine compounds and azaborine-containing biarylcarboxamides, and compositions and methods thereof
发明人：LIU SHIH-YUAN; ZHAO PENG; BROWN ALEC NATHANIEL
权利人:THE TRUSTEES OF BOSTON COLLEGE
摘要:The invention provides novel azaborine compounds, methods for their syntheses and functionalization, and various applications thereof. For example, novel azaborine-containing biarylcarboxylic acids and biarylcarboxamides are disclosed herein, which provide the opportunity to be used as therapeutic agents in different diseases. The novel azaborine-containing compounds show unique physical and biological properties when compared to their corresponding all-carbon compounds. Also, disclosed herein are substituted 1,2-dihydro-1,2-azaborine compounds and methods for making the same including methods for the preparation of various substituted azaborines including alkyl, alkenyl, aryl, nitrile, heteroaryl, and fused ring substituents in the presence of B—H, B—Cl, B—O and N—H bonds from Br-substituted azaborines as well as the synthesis of new fused BN-heterocycles.

专利号:US-2003176368-A1
优先权日:2001-09-06
标题:Synthesis of epothilones, intermediates thereto and analogues thereof
发明人：DANISHEFSKY SAMUEL J; BISWAS KAUSTAV; CHAPPELL MARK; LIN HONG; NJARDARSON JON T; LEE CHUL BOM; RIVKIN ALEXY; CHOU TING-CHAO
摘要:The present invention provides compounds of formula (I): n n n as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

专利号:US-7012142-B2
优先权日:2000-10-27
标 题:Process for preparation of bicyclic and polycyclic molecules
发明人：PERLMUTTER PATRICK; ROSE MARK; THIENTHONG NEERANAT
权利人:UNIV MONASH
摘要:The present application is directed to a method of synthesis of a bicyclic or polycyclic compound of formula I or formula II: n n nin which E, G, Y, n, m, R, R 1 , R 2 , R 3 , R 6 , R 7 , R 8 and R 9 are as defined.

专利号:WO-2010113188-A1
优先权日:2009-03-31
标题 :Fluorurated siliconic polymer, synthesis method and use
发明人：CAPORICCIO GERARDO; MANIERO FRANCESCO; BEVILACQUA MARCO
权利人:MAFLON S R L; CAPORICCIO GERARDO; MANIERO FRANCESCO; BEVILACQUA MARCO
摘要:The present invention relates to a fluorurated siliconic polymer with controlled molecular weight and viscosity having a structure composed by means of the chaining of oligo-dialkylsiloxane building-blocks having a limited and selected molecular weight and alternated mainly with siloxane units containing a fluorurated substituent and - to a marginal degree - inert siloxane units or substituted by unsaturated groups. When the latter are present -they are used for subsequent reactions of clamping or cross-linking. The present invention relates, moreover, to a synthesis method of the mentioned polymer and its use.

专利号:US-10906033-B2
优先权日:2016-03-28
标题 :Synthesis and application of chiral substituted polyvinylpyrrolidinones
发明人：HUA DUY H
权利人:UNIV KANSAS STATE
摘要:Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.