CAS: 61218-44-8; (6As,12As)-6H-[1,3]Dioxolo[4',5':5,6]Benzofuro[3,2-C]Chromene-3,6A(12Ah)-Diol

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(3R,4S)-7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chroman-3,4-diol 7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on S-adenosyl-L-methionine 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

📜高丽槐素置于colletotrichum Gloeosporioides体系中,用 乙醇 作为反应溶剂,化学反应生成 6A-羟基高丽槐素,
参考文献:Oxidation Of The Phytoalexin Maackiain To 6,6A-Dihydroxy-Maackiain By Colletotrichum Gloeosporioides
标题:Oxidation Of The Phytoalexin Maackiain To 6,6A-Dihydroxy-Maackiain By Colletotrichum Gloeosporioides
摘要:Phytoalexins Are Low Molecular Weight Antibiotic Compounds Produced By Plants In Response To Infection By Microbes. These Antimicrobial Compounds Are Thought To Provide Resistance To Microbial Invasion And Colonization. (-)Maackiain And Its Pterocarpan Relatives Can Be Oxidized At A Number Of Sites,Including At The 6A Carbon. A Previously Unknown Metabolite Was Produced From (-)Maackiain By The Broad Host-Range Pathogen Colletotrichum Gloeosporioides (Glomerella Cingulata). This Unknown Was Identified By Lcms-Ms And NMR Spectroscopy To Be 6,6A-Di-Oh-Maackiain (3,6,6A-Trihydroxy-8,9-Methylenedioxy-Pterocarpan). It Is Produced By Isolates That Represent All Four Races And Pathotypes Of C. Gloeosporioides Isolated From The Tropical Forage Legume Stylosanthes Spp. We Present Evidence That The Primary Metabolite (-)6A-Oh-Maackiain Is Subsequently Hydroxylated At Carbon 6,A Step Resulting In A Compound That Is Increased In Polarity And Decreased In Toxicity Relative To The Parent Compound And (-)6A-Oh-Maackiain. This Further Oxidation May Be Required For Efficient Excretion Or Carbon Source Scavenging. (C) 1997 Elsevier Science Ltd. All Rights Reserved.
DOI:10.1016/s0031-9422(97)00082-4