专利号:US-2025228878-A1 优先权日:2021-10-14 标题:Method for the synthesis of evoc probes 发明人:ALLSWORTH MAX; LABUSCHAGNE CHRISTIAAN 权利人:OWLSTONE MED LTD 摘要:A process for the synthesis of a glycoside, comprising the step of;n performing hydrolysis of a methyl ester glycoside in the presence of a base in water, to form a glycoside,n nwherein the propensity to reform the methyl ester glycoside is reduced. The invention also extends to methods for the detection or prognosis of cancer using a glycoside obtained by said process
专利号:US-6313297-B1 优先权日:1998-01-17 标题:Base-catalyzed synthesis of 1-aryl-4-(aryl ethyl)piperazines from aromatic olefins and 1-arylpiperazines 发明人:HERWIG JUERGEN; BELLER MATTHIAS; BREINDL CLAUDIA 权利人:AVENTIS RES & TECHNOLOGIES; GMBH & CO KG 摘要:A process for preparing a 1-aryl-4-(arylethyl)piperazine of the formula (I)by reacting a 1-arylpiperazine of the formula (II)with an aromatic olefin of the formula (III)in an inert solvent in the presence of at least one basic catalyst, where in the formulae (I) to (III)Ar and Ar' independently of one another are an aryl radical, selected from the group of the fused and unfused C6-C22-aromatics and the fused or unfused C5-C22-heteroaromatics which have at least one nitrogen, oxygen or sulfur atom in the ring; andR1 and R2 independently of one another are a hydrogen atom, a C1-C8-alkyl radical or an aryl radical Ar.
专利号:US-6562844-B2 优先权日:1998-01-23 标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation 发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC 权利人:UPJOHN CO 摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:EP-4416163-A1 优先权日:2021-10-14 标题:Method for the synthesis of evoc probes
专利号:US-7002020-B1 优先权日:1998-01-23 标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation 发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V 权利人:UPJOHN CO 摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:WO-2023062386-A1 优先权日:2021-10-14 标题 :Method for the synthesis of evoc probes
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合成参考文献
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