CAS: 529-84-0; 6,7-Dihydroxy-4-Methyl-2H-Chromen-2-One

该化合物是一种显著应用于有机合成和光化研究的丙丙烯衍生物,该化合物具有很强的荧光特性,在生化和分析研究中作为荧光探针很有价值,其结构与Esculetin相似,使它能作为合成更复杂的丙氨基分子的关键中间体. 4-甲基丙基丙烯也研究其潜在的抗氧化和铬化特性.该化合物的特点是纯度和稳定性高,确保研究环境的可靠性能.其定义明确的化学特性和多功能使它成为调查反应机制和开发新光化应用的有用工具.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号533-73-3 1,2,4-苯三酚 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号613-03-6 1,2,4-三乙酰氧基苯 | CAS号116577-51-6 4-methyl-2-oxo-... | CAS号305-01-1 秦皮乙素 | CAS号67-68-5 二甲基亚砜 | CAS号6345-62-6 6-Hydroxy-7-met... | CAS号2555-28-4 7-甲氧基-4-甲基香豆素 | CAS号90-33-5 4-甲基伞形酮 | CAS号674-82-8 双乙烯酮 | CAS号55939-28-1 6,7-二乙酰氧基-4-甲基香豆素 | CAS号4281-40-7 6,7-二甲氧基-4-甲基香豆素 | CAS号3374-03-6 2H-1-Benzopyran... | CAS号6345-62-6 6-Hydroxy-7-met... | CAS号30211-36-0 9-methyl-2,3-di... | CAS号29334-07-4 硫马林

合成工艺路线路线简述

    7-甲氧基-4-甲基香豆素置于吡啶,Sodium Hydroxide,Dipotassium Peroxodisulfate,氢碘酸,乙酸酐体系中,化学反应生成 4-甲基七叶苷原
    参考文献:Bhavsar; Desai,Indian Journal Of Pharmacy,1951,Vol. 13,P. 200,203
    标题:Bhavsar; Desai,Indian Journal Of Pharmacy,1951,Vol. 13,P. 200,203

    海关参考信息

    专利信息


    专利号:US-7598291-B2
    优先权日:2004-09-02
    标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-2010160244-A1
    优先权日:2004-09-02
    标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-6150403-A
    优先权日:1997-10-14
    标 题 :Topical compositions for regulating the oily/shiny appearance of skin
    发明人:BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J
    权利人:PROCTER & GAMBLE
    摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.

    专利号:US-2014328952-A1
    优先权日:2011-12-21
    标题:Topical compositions
    发明人:FLAVIN DANA
    权利人:FLAVIN DANA
    摘要:This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

    专利号:US-8361516-B2
    优先权日:2006-08-03
    标 题:Composition comprising sarsasapogenin
    发明人:LINTNER KARL; MAS CHAMBERLIN CLAIRE
    权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
    摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
    河南氢硅新材料科技有限公司
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    合成参考文献


    摘要:Therapie., 20(879), 1965 []
    摘要:Medicina et Pharmacologia Experimentalis., 17(497), 1967 []
    参考文献:10.1021/jm990073x
    摘要:Muegge I, Martin YC, Hajduk PJ, Fesik SW. Evaluation of PMF scoring in docking weak ligands to the FK506 binding protein. J Med Chem. 1999 Jul 15;42(14):2498–503. doi: 10.1021/jm990073x.
    参考文献:10.1038/nchem.1506
    摘要:Over B, Wetzel S, Grütter C, Nakai Y, Renner S, Rauh D, Waldmann H. Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem. 2013 Jan;5(1):21–8. doi: 10.1038/nchem.1506.
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