CAS: 5284-79-7; 2,6-Bis(4-Azidobenzylidene)-4-Methylcyclohexanone

上下游产品

2,6-bis-[(4-aminophenyl)-methylene]-4-methylcyclohexanone 1-methylcyclohexan-4-one 4-azidobenzaldehyde 4-nitrobenzaldoxime

专利信息

专利号:WO-9102040-A1
优先权日:1989-08-04
标 题:Cyclodextrin labels for nucleic acid and biochemical analysis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention provides a method of qualitative and quantitative nucleic acid sequence analysis using luminescent cyclodextrin (CD), labels for dideoxy-nucleotide chain terminators and oligonucleotide primers. The CD labels are nonradioactive and detected in a ''black'' background, avoiding problems of fluorescence and allowing more sensitivity. Through formation of inclusion complexes with various fluorophores, the CD labels provide the versatility of different colored labels, with potentially higher signal efficiency in aqueous solutions. The CD labels have similar structures and thereby provide simplicity of synthesis and use, with more uniform chemical/physical properties, even with different colored labels. The invention is intended for high volume nucleic sequencing employing photomultipliers or charge-coupled device cameras for detection. Through the combination of these features, this invention provides advantages of speed, sensitivity, simplicity and versatility previously unknown or suggested in the art of nucleic acid sequence analysis.

专利号:US-6048736-A
优先权日:1998-04-29
标 题 :Cyclodextrin polymers for carrying and releasing drugs
发明人：KOSAK KENNETH M
摘要:This invention discloses methods for preparing compositions of cyclodextrin polymers for carrying drugs and other active agents. Methods are also disclosed for preparing cyclodextrin polymer carriers that release drugs under controlled conditions. The invention also discloses methods for preparing compositions of cyclodextrin polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action. The advantages of the water soluble (or colloidal) cyclodextrin polymer carrier are: (1) Drugs can be used that are designed for efficacy without conjugation requirements. (2) It will allow the use of drugs designed solely for efficacy without regard for solubility. (3) Unmodified drugs can be delivered as macromolecules and released within the cell. (4) Drugs can be targeted by coupling the carrier to biorecognition molecules. (5) Synthesis methods are independent of the drug to facilitate multiple drug therapies.

专利号:RU-2586214-C2
优先权日:2011-11-17
标题 :Superabsorbent polymers capable of fast absorption and synthesis method thereof