专利号:WO-0158995-A1 优先权日:2000-02-11 标题 :Thermal insulation material 发明人:SMITH ANDREW JOHN; PLAYER WILLIAM HENRY 权利人:WINN & COALES INTERNAT LTD; SMITH ANDREW JOHN; PLAYER WILLIAM HENRY 摘要:A material for thermal insulation which comprises a phenolic resin, characterised in that one or more fillers and one or more minerals are included as additives during synthesis of the phenolic resin; the one or more fillers being selected from the group consisting of alkaline earth metal sulphates and alkaline earth metal oxides, and the one or more minerals being selected from the group consisting of mica, igneous rock and minerals derivable from igneous rock. Processes for production of such a material and its use as a fire retardant material are also described.
专利号:US-7993390-B2 优先权日:2002-02-08 标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation 发明人:MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN 权利人:BOSTON SCIENT SCIMED INC 摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
参考文献:10.1038/ncb3255 摘要:Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484–96. 摘要:Ross et al. JASMS 2022; 33; 1061-1072. DOI:10.1021/jasms.2c00111 摘要: 摘要:Journal of Pharmacology and Experimental Therapeutics., 196(478), 1976 []