CAS: 340759-46-8; 6-Aminopyridazine-3-Carbonitrile
该化合物是一种有机化合物,其特征为:六人组成的芳香环环,由六人组成,含有两个氮原子的芳香热循环;在六人组和三人组(-CN)中存在一个氨基组(-NH2),有助于其在药用化学和有机合成中的回活动及其潜在应用;该化合物一般表现出功能组的极性特征,这些功能组会影响其在各种溶剂中的溶解性;其分子结构允许氢结合,使其成为与生物目标互动的候选体;该化合物还可能由于存在该环形组而参与核细胞生殖器替代反应;
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海关参考信息
- 2926909090-其他腈基化合物
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专利信息
专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.
