专利号:US-2023109627-A1 优先权日:2019-11-14 标 题:Precursor chemistry for quantum dot synthesis enabling temperature-independent modulation of reactivity 发明人:HAN HEE-SUN; PARK JOONHYUCK 权利人:UNIV ILLINOIS 摘要:Provided herein are methods of making a high-quality quantum dot (QD), including by providing anion precursor chemistry that enables chemical modulation of precursor reactivity, thereby, allowing independent optimization of reaction temperature and precursor reactivity to systematically grow high quality QDs and by providing specially configured tunable precursors and related chemistry to facilitate separate reaction pathways for nucleation and growth, thereby accessing heat-up based synthesis of high-quality QD, including core-shell QDs. The methods may include providing a base-QD and a first anion or cation precursor having a composition comprising an anion or a cation element, respectively, and a modification agent. At least one add-layer is grown on the base-QD at a growth temperature, thereby making the high-quality QD comprising the base-QD and the at least one add-layer. At least one add-layer may have a composition comprising an add-layer cation element and an add-layer anion element.
专利号:US-5453500-A 优先权日:1994-05-26 标 题:Water-soluble glycosylated derivatives of 1,2-dithiin compounds 发明人:KOREEDA MASATO; SHULL BRIAN K; YANG WU 权利人:UNIV MICHIGAN 摘要:Novel water-soluble mono and disaccharides of 1,2-dithiins, as well as methods for their synthesis and the synthesis of 3,6-bis(hydroxymethyl)-1,2-dithiin, are provided. The water-soluble compounds have useful medicinal applications, e.g., as an antifungal agent or antibacterial agent in a pharmaceutically acceptable carrier.
专利号:US-2022251132-A1 优先权日:2019-06-24 标 题 :Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside 发明人:ZETTERBERG FREDRIK; TYRELL ANDREW; NILSSON ULF; BERGH ANDERS; CUMMINS JONATHAN; WEYMOUTH-WILSON ALEXANDER; CLARKSON ROBERT 权利人:GALECTO BIOTECH AB 摘要:The present invention relates to a process for preparing a compound of formula (I) n n n n n n n n n n wherein said process is suitable for large scale synthesis.
专利号:US-9708336-B2 优先权日:2014-01-22 标题 :Metallo-beta-lactamase inhibitors 发明人:MANDAL MIHIR; TANG HAIFENG; XIAO LI; SU JING; LI GUOQING; YANG SHU-WEI; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; HICKS JACQUELINE; LOMBARDO MATTHEW; CHU HONG; HAGMANN WILLIAM; PASTERNAK ALEX; GU XIN; JIANG JINLONG; DONG SHUZHI; DING FA-XIANG; LONDON CLARE; BISWAS DIPSHIKHA; YOUNG KATHERINE; HUNTER DAVID N; ZHAO ZHIQIANG; YANG DEXI 权利人:MERCK SHARP & DOHME 摘要:The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.
专利号:WO-2021097217-A1 优先权日:2019-11-14 标题 :Precursor chemistry for quantum dot synthesis enabling temperature-independent modulation of reactivity