CAS: 13984-57-1; Ethyl 4-Acetylbutyrate

该化合物是一种有机化合物,其特性为由六甲酸和5-ox-Hexanoci酸产生的酯性功能组;该化合物一般是无色的淡黄色液体,具有水果味,在各酯中常见;在有机溶剂中可溶解,由于其对水的碳氢化合物链,水溶解性有限;各种化学品,调味剂和芳香的合成中经常使用乙酸衍生物;其结构中含有基类(5-oxo),可影响其再活性和有机合成的潜在应用;此外,与许多酯一样,它可能在水中进行水解,并恢复到其母酸和酒精;在处理和接触准则方面,应参考安全数据,如任何化学物质,以确保在实验室或工业环境中使用时采取适当的安全措施.

结构式图片

相似化合物

3128-06-1 21856-89-3 20266-62-0

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号34495-74-4 (E)-hex-4-enoic... | CAS号4761-26-6 丁酰丙二酸二乙酯 | CAS号28483-60-5 tributyl(prop-1... | CAS号140-88-5 丙烯酸乙酯 | CAS号5205-39-0 戊二酸单乙酯酰氯 | CAS号75-16-1 甲基溴化镁 | CAS号1120-72-5 2-甲基环戊酮 | CAS号64-17-5 乙醇 | CAS号498-07-7 1,6-脱水-β-D-葡萄糖 | CAS号78-94-4 丁烯酮 | CAS号332884-21-6 5,6,7,8-四氢-1,8-... | CAS号55170-74-6 5-甲基己基-2-丁烯酸 | CAS号1460-08-8 2-diazonio-3-ox... | CAS号504-02-9 1,3-环己二酮 | CAS号20266-62-0 ethyl 5-hydroxy... | CAS号2610-95-9 6,6-Dimethyltet... | CAS号2768-16-3 5-甲基壬醇 | CAS号823-22-3 丁位己内酯 | CAS号143-07-7 月桂酸 | CAS号103621-30-3 Diethyl (Z)-3-M...

合成工艺路线路线简述

    📜乙酰戊二酸二乙酯置于盐酸体系中,化学反应生成4-乙酰基丁酸乙酯
    参考文献:3,7-二甲基-辛二烯-(2,7)-Säure-(1)和5-甲基-己烯-(5)-Säure-(1)的合成和环化
    标题:3,7-二甲基-辛二烯-(2,7)-Säure-(1)和5-甲基-己烯-(5)-Säure-(1)的合成和环化
    摘要:A.3,7-二甲基辛二烯-(2,7)-Säure-(1)(天竺葵(limonenform Dergeraniumsäure))由5甲基-己烯-(5)-Säure-(1)über6-甲基-庚烯-(6)-(2)上的乙酰丙酮法赫氏酯.
    Doi:10.1002/hlca.19540370403

    海关参考信息

    专利信息


    专利号:US-6107495-A
    优先权日:1996-07-24
    标题:Thienylcyclohexane derivatives for thienylcyclohexyl synthesis
    发明人：CAZAUX JEAN-BERNARD; DAFNIET MICHEL; KAMENKA JEAN-MARC; MANGINOT ERIC
    权利人:EXPANSIA SA
    摘要:PCT No. PCT/FR97/01382 Sec. 371 Date Jan. 19, 1999 Sec. 102(e) Date Jan. 19, 1999 PCT Filed Jul. 24, 1997 PCT Pub. No. WO98/03498 PCT Pub. Date Jan. 29, 1998Novel thienylcyclohexane derivatives of general formula (I), wherein R' is the 2-thienyl or 3-thienyl radical, R is the cyano radical or a radical of formula -C(O)A, and R2'' is a saturated or unsaturated optionally cyclic hydrocarbon radical, or an aryl radical, are disclosed. Methods for preparing said compounds, and the use thereof as novel industrial products for the synthesis of thienylcyclohexyl derivatives, are also disclosed.

    专利号:WO-02064579-A1
    优先权日:2001-02-09
    标题 :Method for producing optically active, propargylic terminal epoxides
    发明人：SCHUBERT THOMAS A; HUMMEL WERNER; MUELLER MICHAEL
    权利人:FORSCHUNGSZENTRUM JUELICH GMBH; SCHUBERT THOMAS A; HUMMEL WERNER; MUELLER MICHAEL
    摘要:The invention relates to a method for enantioselective representation of optically active, propargylic, terminal epoxides. According to the invention, in a first step of the inventive method, compounds of formula I are reacted with an alcoholdehydrogenase which preferably originates from horse liver or thermophilic microorganisms (e.g. thermoanaerobium brockii or thermoanaerobacter ethanolicus) or from Lactobacillus and is recombina ntly overexpressed in Escherichia coli , in the presence of NAD (P) H. During said reaction, the oxogroup is enantioselectively reduced. Since ( S ) selective and ( R ) selective oxido reductases can be used, the synthesis of both enantiomers is possible. Representation of both enantiomers using the same enzyme is achieved with alkoholdehydrogenase from Lactobacillus brevis , since said compounds react with R<1> = H and compounds with R<1> = H to form alcohols having an opposite configuration. In the second step of the method, the alpha -halogenated alcohol is transformed into an enantiomer pure epoxide by means of a base.

    专利号:US-5521179-A
    优先权日:1991-04-18
    标题 :Heterocyclic amides
    发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
    权利人:ZENECA LTD
    摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.

    专利号:CN-107876092-A
    优先权日:2017-11-24
    标 题 :High Stability Titanium Catalyst for the Synthesis of Benzyl Carbonate and Diphenyl Carbonate by Transesterification

    专利号:FR-2751652-A1
    优先权日:1996-07-24
    标题 :THIENYLCYCLOHEXANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS NEW INDUSTRIAL PRODUCTS FOR THE SYNTHESIS OF THIENYLCYCLOHEXYL DERIVATIVES

    专利号:ES-2227710-T3
    优先权日:1996-07-24
    标 题 :DERIVATIVES OF TIENILCICLOHEXANO FOR THE SYNTHESIS OF TIENILCICLOHEXILOS.

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Mno2 As A Terminal Oxidant In Wacker Oxidation Of Homoallyl Alcohols And Terminal Olefins
    作者:Rodney A. Fernandes,Gujjula V. Ramakrishna,Venkati Bethi
    摘要:Pdcl2/cro3/hcl Produced α,β-Unsaturated Ketones From Homoallyl Alcohols, The Present Method Provided Orthogonally The β-Hydroxy-Methyl Ketones. No Overoxidation Or Elimination Of Benzylic And/or β-Hydroxy Groups Was Observed. The Method Could Be Extended To The Oxidation Of Simple Terminal Olefins As Well, To Methyl Ketones, Displaying Its Versatility. An Application To The Regioselective Synthesis Of Gingerol Is

    合成参考文献


    摘要:De Wildeman, S.; Sereinig, N., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 169.
    摘要:Simon, R. C.; Busto, E.; Fischereder, E.-M.; Fuchs, C. S.; Pressnitz, D.; Richter, N.; Kroutil, W., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 394.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知