CAS: 13749-61-6; N-Isopropylmethacrylamide

该化合物是一种合成化合物,其特征为氨化功能组和甲基丙烯酸结构,使其成为甲基丙烯酸盐家族的成员;一种在有机溶剂中溶解但水溶性有限的黄色清色液体,无色无色无色可染;NIPMAM的热反应性能值得注意,它允许它随着温度变化而经历一个阶段的过渡,使其在各种应用中有用,包括药物运载系统,组织工程和智能材料;该化合物可以聚合成水凝胶,因为生物兼容性以及对环境刺激性反应的能力,对生物医学应用具有重大兴趣.此外,NIPMAM可与其他单体共同聚合,以调整由此产生的聚合物的特性,用于特定用途.安全数据表明,与许多化学物质一样,应谨慎处理,使用适当的个人防护设备尽量减少接触.

结构式图片

相似化合物

3887-02-3 2210-25-5 107-58-4

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REACH注册ECHA物质C&L通报REACH预注册

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CAS号760-93-0 甲基丙烯酸酐 | CAS号75-31-0 异丙胺 | CAS号920-46-7 甲基丙烯酰氯 | CAS号282097-60-3 3-dimethylamino... | CAS号107-05-1 氯丙烯 | CAS号80-62-6 甲基丙烯酸甲酯 | CAS号67-63-0 异丙醇 | CAS号126-98-7 甲基丙烯腈

合成工艺路线路线简述

    异丙醇,甲基丙烯腈置于硫酸,铜,对苯二酚体系中,化学反应生成N-异丙基甲基丙烯酰胺
    参考文献:Production Of Nu-Isopropylmethacrylamide
    标题:Production Of Nu-Isopropylmethacrylamide

    海关参考信息

    专利信息


    专利号:US-8669356-B2
    优先权日:2009-10-21
    标 题 :Linker and support for solid phase synthesis of nucleic acid
    发明人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA
    权利人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA; NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP
    摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae n nwherein each symbol is as defined in the specification.

    专利号:US-6610802-B2
    优先权日:2001-05-29
    标题 :Process for synthesis of polymer compositions, polymer compositionS obtainable by the process, and use of the same
    发明人:ROOS SEBASTIAN; EISENBERG BORIS; HARPE CAROLIN
    权利人:ROHMAX ADDITIVES GMBH
    摘要:The present invention relates to a process for synthesis of polymer compositions with reduced catalyst content, wherein ethylenically unsaturated monomers containing less than 0.5 wt % of ethylenically unsaturated monomers with at least one carboxylic group, sulfonic acid group and/or at least one phosphonic acid group relative to the total weight of the ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts and, after the polymerization, the catalyst contained in the polymer is at least partly separated. For this purpose, the polymer composition is filtered, after the polymerization, in the presence of at least one filter aid which contains at least 0.5 wt %, relative to the total weight of the filter aid, of repeating units that contain at least one carboxylic acid group, sulfonic acid group and/or at least one phosphonic acid group.

    专利号:US-6610801-B1
    优先权日:2000-11-13
    标题:Processes for synthesis of polymer compositions
    发明人:SCHERER MARKUS
    权利人:ROHMAX ADDITIVES GMBH
    摘要:The present invention relates to processes for synthesis of poly(meth)acrylate compositions, wherein ethylenically unsaturated monomers are transformed to polymers by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, wherein ethylenically unsaturated monomers containing 50 to 100 wt %, relative to the total weight of ethylenically unsaturated monomers, of (meth)acrylates of formula (I) are polymerizedwherein R denotes hydrogen or methyl, R1 denotes a straight-chain or branched alkyl group with 8 to 40, carbon atoms, R2 and R3 independently denote hydrogen or a group of the formula -COOR1, wherein R' denotes hydrogen or a straight-chain or branched alkyl group with 8 to 40, carbon atoms, in the presence of copper, the total concentration of copper of oxidation numbers (I) and (II) in the polymerization composition being <=200 ppm relative to the total weight of the composition.

    专利号:US-6639029-B1
    优先权日:2000-11-13
    标 题 :Process for continuous synthesis of polymer compositions as well as use of same
    发明人:SCHERER MARKUS; BOLLINGER JOSEPH MARTIN; COOPER JR DAVID J; TILLERY LARRY STEPHEN; WOODRUFF ROBERT
    权利人:ROHMAX ADDITIVES GMBH
    摘要:The present invention relates to a process for synthesis of polymer compositions, wherein ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable atom or group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, the process being characterized in that the polymerization takes place by means of continuous process operation.

    专利号:US-8835656-B2
    优先权日:2012-01-30
    标 题 :Linker and support for solid phase synthesis of nucleic acid
    发明人:TSUKAMOTO MASAKI; SUZUKI NORITAKA; HAYAKAWA YOSHIHIRO; MAETA ERI; MORI KENJIRO; MINOMI KENJIRO
    权利人:NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP
    摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker contains a compound represented by the formula n nwherein each symbol is as defined in the specification.

    专利号:US-2009263858-A1
    优先权日:2004-09-14
    标 题 :Process for synthesis of mucin-type peptides and muc1-related glycopeptides
    发明人:NISHIMURA SHINICHIRO; HINOU HIROSHI; FUMOTO MASATAKA
    权利人:SHIONOGI & CO
    摘要:The invention aims at providing novel compounds useful as primer in producing mucin-type glycopeptides which are useful in a wide field including materials for biochemical research, drugs, and food and the production of which was difficult in the prior art; and a process for the production of glycopeptides by using the primers. The aim is attained by providing novel glycopeptide derivatives (represented by the general formula (I)) which each bear an aldehyde or ketone group at the end and each contain an amino acid residue cleavable with a protease; and an easy and simple process for the production of glycopeptides by using the derivative as the primer.
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    主要参考文献

    [参考文献]: Shalini Saxena, Et Al. Influence Of Binary Microgel Phase Behavior On The Assembly Of Multi-Functional Raspberry-Structured Microgel Heteroaggregates. J Colloid Interface Sci. 2015 Oct 1:455:93-100.

    合成参考文献


    摘要:Mace Weldy, N.; Blakey, S. B., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 284.
    摘要:Compound: N-Isopropylmethacrylamide homopolymer
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