专利号:US-8669356-B2 优先权日:2009-10-21 标 题 :Linker and support for solid phase synthesis of nucleic acid 发明人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA 权利人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA; NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP 摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae n nwherein each symbol is as defined in the specification.
专利号:US-6610802-B2 优先权日:2001-05-29 标题 :Process for synthesis of polymer compositions, polymer compositionS obtainable by the process, and use of the same 发明人:ROOS SEBASTIAN; EISENBERG BORIS; HARPE CAROLIN 权利人:ROHMAX ADDITIVES GMBH 摘要:The present invention relates to a process for synthesis of polymer compositions with reduced catalyst content, wherein ethylenically unsaturated monomers containing less than 0.5 wt % of ethylenically unsaturated monomers with at least one carboxylic group, sulfonic acid group and/or at least one phosphonic acid group relative to the total weight of the ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts and, after the polymerization, the catalyst contained in the polymer is at least partly separated. For this purpose, the polymer composition is filtered, after the polymerization, in the presence of at least one filter aid which contains at least 0.5 wt %, relative to the total weight of the filter aid, of repeating units that contain at least one carboxylic acid group, sulfonic acid group and/or at least one phosphonic acid group.
专利号:US-6610801-B1 优先权日:2000-11-13 标题:Processes for synthesis of polymer compositions 发明人:SCHERER MARKUS 权利人:ROHMAX ADDITIVES GMBH 摘要:The present invention relates to processes for synthesis of poly(meth)acrylate compositions, wherein ethylenically unsaturated monomers are transformed to polymers by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, wherein ethylenically unsaturated monomers containing 50 to 100 wt %, relative to the total weight of ethylenically unsaturated monomers, of (meth)acrylates of formula (I) are polymerizedwherein R denotes hydrogen or methyl, R1 denotes a straight-chain or branched alkyl group with 8 to 40, carbon atoms, R2 and R3 independently denote hydrogen or a group of the formula -COOR1, wherein R' denotes hydrogen or a straight-chain or branched alkyl group with 8 to 40, carbon atoms, in the presence of copper, the total concentration of copper of oxidation numbers (I) and (II) in the polymerization composition being <=200 ppm relative to the total weight of the composition.
专利号:US-6639029-B1 优先权日:2000-11-13 标 题 :Process for continuous synthesis of polymer compositions as well as use of same 发明人:SCHERER MARKUS; BOLLINGER JOSEPH MARTIN; COOPER JR DAVID J; TILLERY LARRY STEPHEN; WOODRUFF ROBERT 权利人:ROHMAX ADDITIVES GMBH 摘要:The present invention relates to a process for synthesis of polymer compositions, wherein ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable atom or group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, the process being characterized in that the polymerization takes place by means of continuous process operation.
专利号:US-8835656-B2 优先权日:2012-01-30 标 题 :Linker and support for solid phase synthesis of nucleic acid 发明人:TSUKAMOTO MASAKI; SUZUKI NORITAKA; HAYAKAWA YOSHIHIRO; MAETA ERI; MORI KENJIRO; MINOMI KENJIRO 权利人:NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP 摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker contains a compound represented by the formula n nwherein each symbol is as defined in the specification.
专利号:US-2009263858-A1 优先权日:2004-09-14 标 题 :Process for synthesis of mucin-type peptides and muc1-related glycopeptides 发明人:NISHIMURA SHINICHIRO; HINOU HIROSHI; FUMOTO MASATAKA 权利人:SHIONOGI & CO 摘要:The invention aims at providing novel compounds useful as primer in producing mucin-type glycopeptides which are useful in a wide field including materials for biochemical research, drugs, and food and the production of which was difficult in the prior art; and a process for the production of glycopeptides by using the primers. The aim is attained by providing novel glycopeptide derivatives (represented by the general formula (I)) which each bear an aldehyde or ketone group at the end and each contain an amino acid residue cleavable with a protease; and an easy and simple process for the production of glycopeptides by using the derivative as the primer.
[参考文献]: Shalini Saxena, Et Al. Influence Of Binary Microgel Phase Behavior On The Assembly Of Multi-Functional Raspberry-Structured Microgel Heteroaggregates. J Colloid Interface Sci. 2015 Oct 1:455:93-100.
合成参考文献
摘要:Mace Weldy, N.; Blakey, S. B., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 284. 摘要:Compound: N-Isopropylmethacrylamide homopolymer