CAS: 66990-30-5; 10,12-Tricosadiynoicacid

上下游产品

CAS号2777-65-3 10-十一碳炔酸 | CAS号118869-25-3 1-chlorododec-1-yne | CAS号60705-20-6 1-iodododec-1-yne | CAS号145609-79-6 10,12-二十三碳二炔酸甲酯

📜10-十一碳炔酸,1-碘十二碳-1-炔 反应生成 10,12-二十三联炔酸
参考文献:Tieke,B. Et Al.,Angewandte Chemie,1976,Vol. 88,P. 805-806
标题:Tieke,B. Et Al.,Angewandte Chemie,1976,Vol. 88,P. 805-806

专利信息

专利号:US-6355490-B1
优先权日:1996-09-13
标题:Attached tags for use in combinatorial chemistry synthesis
发明人：HOCHLOWSKI JILL EDIE; SOWIN THOMAS J; NORBECK DANIEL W; GRILLOT ANNE-LAURE MARIE; SWENSON ROLF E
摘要:The present invention relates to a process of coding and identifying individual members of a chemical combinatorial library synthesized on a plurality of solid supports which undergo mix and split synthesis. The process provides for tagging the solid supports with a coding identifier that is attached to the solid support and which can be decoded by infrared or raman spectroscopy when directly attached to the support.

专利号:WO-8801280-A1
优先权日:1986-08-21
标 题:Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion
发明人：NICOLSON GARTH L; IRIMURA TATSURO; NAKAJIMA MOTOWO
权利人:UNIV TEXAS
摘要:Method for impeding the formation of tumor metastasis or tumor invasiveness in a host. Such inhibition comprises administration to the host of a glycosaminoglycan derivative substantially devoid of anticoagulation activity and is an effective inhibitory of heparanase activity. Such a glycosaminoglycan derivative may be provided by purchase or synthesis as directed herein. Parenteral administration to a tumor-bearing host of the glycosaminoglycan derivative results in the exposure of host-borne tumor cells thereto. Such exposure to effective levels of the derivative results in the inhibition of tumor heparanase activity and a lessening of invasiveness and metastatic spread. Heparin, a glycosaminoglycan particularly effective as a heparanase inhibitor and an anti-clotting agent, is a preferred glycosaminoglycan for derivatization. Upon derivatization according to the present invention heparin may be converted into a glycosaminoglycan derivative substantially devoid of anticoagulant activity but yet being an effective inhibitor of heparanase activity. Mere reduction of heparin carboxyl groups results in the production of a glycosaminoglycan derivative inhibitory to heparanase activity but without substantially anticoagulant activity non-anticoagulating, heparanase-inhibiting glycosaminoglycan derivatives may also be prepared from heparin, for example, by: at least partial N-desulfation and then N-acetylation; or N-, O-desulfation followed by N-resulfation.

专利号:US-10246405-B2
优先权日:2011-06-07
标题 :Porous diacetylene particles, synthesis method thereof
发明人：AHN DONG JUNE; YANG DOO HO
权利人:UNIV KOREA RES & BUS FOUND
摘要:Provided are a radial porous diacetylene particle, which is synthesized by ion-bonding a diacetylene-containing dicarboxylic acid or diamine monomer represented by Formula 1 with a diamine or dicarboxylic acid monomer represented by Formula 2, and a method of manufacturing the same.