专利号:US-4751312-A 优先权日:1984-07-20 标 题:Process and intermediates for the synthesis of diastereomeric compounds 发明人:GASTEIGER JOHANN; KAUFMANN KARLHEINZ; MENGEL RUDOLF 权利人:BAYER AG 摘要:A new process for the controlled synthesis of the two diasteromeric forms of triazolyl-O,N-acetals of the formula (I) in which R represents optionally substituted phenyl, optionally substituted phenoxy, optionally substituted alkoxy, optionally substituted alkoxy, optionally substituted alkylthio, alkylcarbonyl, nitro or halogen and n represents an integer from 0 to 5, with the proviso that R can represent identical or different radicals, if n represents an integer from 2 to 5. New trans-substituted oxiranes and their use as intermediates for the synthesis of compounds of the formula (I).
专利号:US-5403937-A 优先权日:1993-04-30 标 题 :Process for preparing intermediates for the synthesis of antifungal agents 发明人:SAKSENA ANIL K; GIRIJAVALLABHAN VIYYOOR M; PIKE RUSSELL E; WANG HAIYAN; LOVEY RAYMOND G; LIU YI-TSUNG; GANGULY ASHIT K; MORGAN WILLIAM B; ZAKS ALEKSEY 权利人:SCHERING CORP 摘要:Disclosed is a process for preparing chiral compounds of the formula (I) (I) wherein: X1 and X2 are independently F or Cl; and E is -SO2R2, wherein R2 is C1-C6 alkyl, -C6H4CH3 or -CF3; its enantiomer and racemates thereof, useful in the synthesis of tetrahydrofuran azole antifungals. Novel compounds of the formula or wherein: X1 and X2 are independently F or Cl; B represents -C(O)Q* or -CH2OR''; Q* represents a chiral auxiliary group; R'' represents a hydroxy protecting group selected from -CH2C6H5, or -C(O)R1, wherein R1 is C1-C6 alkyl; and A represents Cl, Br, I or triazolyl; are also disclosed.
专利号:WO-9425452-A1 优先权日:1993-04-30 标 题 :Process for preparing intermediates for the synthesis of antifungal agents
专利号:DE-69419505-T2 优先权日:1993-04-30 标题 :METHOD FOR THE PRODUCTION OF INTERMEDIATE PRODUCTS FOR THE SYNTHESIS OF ANTIMYCOTICS
专利号:DD-237836-A5 优先权日:1984-07-20 标 题:PROCESS FOR SYNTHESIS OF THE DIASTEROMIC FORMS OF TRIAZOLYL-O, N-ACETALES
专利号:EP-0169439-B1 优先权日:1984-07-20 标 题 :Process for and intermediates in the synthesis of diastereomeric triazolyl-o,n-acetals