CAS: 40298-71-3; (S)-2-((Tert-Butoxycarbonyl)Amino)-3-(4-((2,6-Dichlorobenzyl)Oxy)Phenyl)Propanoic Acid

相似化合物

112402-12-7 2130-96-3 63769-58-4

上下游产品

CAS号85842-19-9 N-tert-Butoxyca... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号40298-69-9 HL-Tyr(2,6-Cl2-... | CAS号3978-80-1 N-B°C-L-酪氨酸 | CAS号58822-25-6 [Leu5]-脑啡肽 | CAS号60-18-4 L-酪氨酸 | CAS号141801-26-5 内吗啡-2 | CAS号169393-62-8 B°C-(S)-2-AMINO... | CAS号79985-48-1 Dynorphin A (1-...

📜N-Tert-Butoxycarbonyl-O-2,6-Dichlorbenzyl-(S)-Tyrosin Methylester置于sodium Hydroxide体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 1.33H,反应生成 丁氧羰基-O-2,6-二氯苄基-L-酪氨酸
参考文献:酯碱水解的简单方法
标题:酯碱水解的简单方法
摘要:通过使用二氯甲烷/甲醇(9:1)作作为反应溶剂,已经开发出一种非常温和,快速的方法,可在非水条件下有效地进行酯的碱性水解.该方法可在室温下几分钟内方便地由相应的酯和氢氧化钠提供羧酸和醇.提出了合理的反应机理.
DOI:10.1016/j.Tetlet.2007.09.074

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-3988308-A
优先权日:1974-11-04
标题 :(Tyr3, Tyr14)-SRIF and intermediates
发明人：SARANTAKIS DIMITRIOS
权利人:AMERICAN HOME PROD
摘要:The tetradecapeptide Ala-Gly-Tyr-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Tyr-OH is described as well as novel intermediates used in the synthesis of such tetradecapeptide. This tetradecapeptide inhibits the release of growth hormone.

专利号:US-3941763-A
优先权日:1975-03-28
标题:PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
发明人：SARANTAKIS DIMITRIOS
权利人:AMERICAN HOME PROD
摘要:The synthesis of the decapeptide pGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 by solid-phase techniques is described. The decapeptide inhibits LH release.

专利号:US-4415493-A
优先权日:1982-05-11
标 题 :Immune modulator peptides
发明人：WEIGLE WILLIAM O; MORGAN EDWARD L
权利人:SCRIPPS CLINIC RES
摘要:A class of 23 or 24 amino acid peptides available by chemical synthesis or by enzymatic and chemical cleavage of IgG is described. The compounds are useful in modulating the immune response.