其它别名N,N'-Bis(Acryloyl)-1,2-Diaminoethane, Stabilized With 0.1% Hydroquinone; N,N'-(Ethane-1,2-Diyl)Diacrylamide; Ethylene Bis Acrylamiden,N'-Ethane-1,2-Diylbisacrylamide
专利号:US-4753985-A 优先权日:1981-10-07 标题 :Synthesis of organic compounds using deformable gel in porous rigid support 发明人:ROSEVEAR ALAN; SHEPPARD ROBERT C 权利人:ATOMIC ENERGY AUTHORITY UK 摘要:The present invention relates to the synthesis of chemical compounds and more particularly to the synthesis of organic compounds, for example, peptides and oligonucleotides. n The invention provides a composite material for use in the synthesis of organic compounds comprising a support material and, supported on the support material, an organic compound synthesizing substance. n It is preferred that the organic compound synthesizing substance is a gel (e.g. a dimethylacrylamide co-polymer gel). n The invention also provides a method for preparing a composite material for use in the synthesis of organic compounds and a method for the synthesis of organic compounds.
专利号:US-2004152905-A1 优先权日:2003-01-31 标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs 发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH 摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.
专利号:US-2004242897-A1 优先权日:2002-07-31 标题 :Universal support media for synthesis of oligomeric compounds 发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH 摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.
专利号:US-2003182068-A1 优先权日:2001-10-30 标 题 :Device and methods for directed synthesis of chemical libraries 发明人:BATTERSBY BRONWYN J; MILLER CHRISTOPHER R; TRAU MATHIAS; WAY JEFFERY C; JOHNSTON ANGUS 摘要:The invention features a sort computer which interfaces with a sorting device in order to control the sorting of beads on a bead by bead basis. The invention further features novel methods for the directed synthesis of encoded libraries of oligomers, e.g., oligonucleotides, on beads. These methods allow the synthesis of libraries that are sufficiently large to permit complex genomic analyses to be carried out. New methods of using the encoded libraries also are described.
专利号:WO-2004011474-A1 优先权日:2002-07-31 标题:Universal support media for synthesis of oligomeric compounds 发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K 权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K 摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.
专利号:US-6653468-B1 优先权日:2002-07-31 标 题 :Universal support media for synthesis of oligomeric compounds 发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH 权利人:ISIS PHARMACEUTICALS INC 摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.
参考标题:Universal Building Blocks And Support Media For Synthesis Of Oligonucleotides And Their Analogs 摘要:Compounds For The Synthesis Of Oligomeric Compounds, Particularly Oligonucleotides And Chemically Modified Oligonucleotide Analogs, Are Provided. In Addition, Methods For Functionalization Of A Support Medium With A First Monomeric Subunit And Methods For The Synthesis Of Oligomeric Compounds Utilizing The Novel Compounds Bound To Support Media Are Provided.
合成参考文献
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