CAS: 28983-56-4; [[4-[bis[4-[(Sulfophenyl)Amino]Phenyl]Methylene]-2,5-Cyclohexadien-1-Ylidene]Amino]-Benzenesulfonic Acid Sodium Salt (1:2)

专利信息

专利号:US-2018171086-A1
优先权日:2016-12-16
标题 :Large area monolayer of perfluoro polymers
发明人：SUN HAORAN
权利人:SOUTH DAKOTA BOARD OF REGENTS
摘要:Synthesis and growth of large area free-standing ultra-thin two-dimensional (2D) polymeric films including 2D covalent organic frameworks (COF) are achieved by utilizing fluorocarbon-soluble fluorinated aldehyde derivatives and hydrocarbon-soluble amine derivatives at a liquid-liquid interface of respective fluorocarbon and hydrocarbon solvents.

专利号:US-2005080260-A1
优先权日:2003-04-22
标 题 :Preparation of prodrugs for selective drug delivery
发明人：MILLS RANDELL L; WU GUO-ZHANG
摘要:Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. Novel synthetic methods of the present invention to form the prodrug comprised the steps of (1) forming a benzophenone, (2) forming a diaryl ethylene, (3) attaching a phthalimide moiety to at least one of the aryl groups of the ethylene to form a phthalimide-ethylene conjugate, (4) condensing two ethylene-phthalimide conjugates to form a phthalimide-pentadiene conjugate, (5) converting the phthalimide to the phthalhydrazide by reaction with hydrazine to form a carrier compound according to the present invention, and (6) reacting the carrier compound with an nucleophilic moiety of the drug to form the corresponding prodrug. Alternatively the carrier can be prepared by using the halo-substituted diaryl ethylene to make the corresponding cationic leuco dye-like compound with known methods. The cationic compound then is protected by reacting with a nucleophile and coupled with the aminophathalimide by palladium-catalyzed amination to form the protected phthalimide-pentadiene conjugate. The latter is refluxed with hydrazine to convert its phthalimide to the phthalhydrazide and acidified to give the carrier. An additional aspect of the present invention relates to the use of these compounds as antiviral agents for the treatment of viral infections such as HIV and as anticancer agents for the treatment of cancers such as bowel, lung, and breast cancer.

专利号:US-4622400-A
优先权日:1983-12-29
标 题:Preparation of certain m-aminophenols and the use thereof for preparation of laser dyes
发明人：HAMMOND PETER R
权利人:US ENERGY
摘要:Methods are provided for making certain m-aminophenols using a sulfonation/alkali fusion procedure. The aminophenols are key intermediates in the synthesis of dyes, particularly efficient, stable dyes for laser application. Preparations of some rhodamine and phenoxazone dyes from the m-aminophenols are described.

专利号:CN-108659154-B
优先权日:2018-04-25
标题 :Synthesis method and application of pH response type AIE fluorescent nano polymer quantum dots

专利号:CN-108329413-A
优先权日:2017-01-20
标题 :A kind of polyvinyl alcohol sulfonate and its synthesis method, hydrophilic plate for printing and its application and printing plate

专利号:CN-108329445-A
优先权日:2017-01-20
标题:A kind of phenolic resin esterified benzene sulfonate and its synthesis method, hydrophilic plate for printing and its application, and printing plate