CAS: 2660218-70-0; Dgkζ-In-1
- 英文名称Dgkζ-In-1
- 中文名称(S)-N-(2-(3-(氨基甲基)哌啶-1-基)-4-苯氧基-3-(三氟甲基)苯基)-2-(哒嗪-4-基)噻唑-4-甲酰胺
- IUPAC名称(S)-N-(2-(3-(aminomethyl)piperidin-1-yl)-4-phenoxy-3-(trifluoromethyl)phenyl)-2-(pyridazin-4-yl)thiazole-4-carboxamide
- 其它别名N-[2-[(3S)-3-(Aminomethyl)-1-Piperidinyl]-4-Phenoxy-3-(Trifluoromethyl)Phenyl]-2-(4-Pyridazinyl)-4-Thiazolecarboxamide; (S)-N-[2-[3-(Aminomethyl)-1-Piperidyl]-4-Phenoxy-3-(Trifluoromethyl)Phenyl]-2-(4-Pyridazinyl)Thiazole-4-Carboxamide
- CAS编号2660218-70-0
- MFCD编号:0
- FDA UNII编号:BWT5E5YB85
- 分子式:C27H25F3N6O2S分子量:554.6
- 产品CID: 1243994
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2912110000-甲醛
2907121100-间甲酚
2903399090-其他无环烃卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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📌 第三方产品分析报告
主要参考文献
[1]. Watanabe H, et al. Preparation of pyridazinyl-thiazolecarboxamide compound as DGKζ inhibitor. World Intellectual Property Organization, WO2021132422 A1. 2021-07-01.合成参考文献
参考文献:10.1158/1535-7163.mct-23-0108
摘要:Ikeda O, Kikuchi A, Tsuzuki H, Watanabe H, Okuyama K, Seki Y, Ujihara S, Matsuda T, Weng J, Kawashima T, Kiso T, Suzuki A, Nagashima T, Suzuki T, Yamano K, Kawase T, Yoshida T. Enhanced Antitumor Immunity by ASP1570, a Novel Diacylglycerol Kinase ζ Inhibitor, Offers a Potential Novel Immunotherapy for Treating Cancer. Mol Cancer Ther. 2025 Jun 04;24(6):884–95. doi: 10.1158/1535-7163.mct-23-0108.
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