CAS: 2227425-05-8; (S)-3-Chloro-7-(2-(Hydroxymethyl)Morpholino)-2-Methyl-5-(Trifluoromethyl)-1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile
- 英文名称(S)-3-Chloro-7-(2-(Hydroxymethyl)Morpholino)-2-Methyl-5-(Trifluoromethyl)-1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile
- 中文名称(S)-3-氯-7-(2-(羟甲基)吗啉代)-2-甲基-5-(三氟甲基)-1H-B[3,2-B]吡啶-6-甲腈
- IUPAC名称(S)-3-chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
- 其它别名1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile, 3-Chloro-7-[(2S)-2-(Hydroxymethyl)-4-Morpholinyl]-2-Methyl-5-(Trifluoromethyl)-; (S)-3-Chloro-7-(2-(Hydroxymethyl)Morpholino)-2-Methyl-5-(Trifluoromethyl)-1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile
- CAS编号2227425-05-8
- MFCD编号:MFCD31657405
- 分子式:C15H14ClF3N4O2分子量:374.75
- 产品CID: 1153916
物理性质
MSDS等安全信息
上下游产品
ethyl 3-amino-5-methyl-1H-pyrrole-2-carboxylate 7-hydroxy-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile (S)-morpholin-2-ylmethanol 7-chloro-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2909110000-乙醚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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📌 第三方产品分析报告
主要参考文献
1: Shin S, Awuah Boadi E, Bandyopadhyay BC. Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells. Clin Exp Pharmacol Physiol. 2023 Mar;50(3):247-255. doi: 10.1111/1440-1681.13741. Epub 2022 Dec 18.
2: Xue J, Thomas L, Dominguez Rieg JA, Rieg T. Sodium phosphate cotransporter 2a inhibitors: potential therapeutic uses. Curr Opin Nephrol Hypertens. 2022 Sep 1;31(5):486-492. doi: 10.1097/MNH.0000000000000828. Epub 2022 Jul 18.
3: Thomas L, Dominguez Rieg JA, Rieg T. Npt2a as a target for treating hyperphosphatemia. Biochem Soc Trans. 2022 Feb 28;50(1):439-446. doi: 10.1042/BST20211005.
合成参考文献
参考DOI号:10.1021/acsmedchemlett.8b00013
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