CAS: 1721-93-3; 1-Methylisoquinoline

上下游产品

CAS号2412-58-0 1-甲基-3,4-二氢异喹啉 | CAS号119-65-3 异喹啉 | CAS号917-54-4 甲基锂 | CAS号36177-79-4 1-氯甲基-3,4-二氢异喹啉 | CAS号4965-09-7 1-甲基-1,2,3,4-四氢异喹啉 | CAS号102249-88-7 1-cyano-1-methy... | CAS号19493-44-8 1-氯异喹啉 | CAS号1779-49-3 甲基三苯基溴化膦 | CAS号855692-09-0 1-methyl-3,4-di... | CAS号16576-32-2 2-苯甲酰基-1-甲基-1,2... | CAS号4494-18-2 1-异喹啉甲醛 | CAS号126921-66-2 isoquinoline-1-... | CAS号20335-59-5 1-methyl-5-nitr... | CAS号27311-65-5 1-(氯甲基)异喹啉 | CAS号88237-16-5 1-(dichlorometh... | CAS号24613-99-8 2-Benzothiazol-... | CAS号69582-93-0 2-(异喹啉-1-基)乙酸甲酯 | CAS号7661-60-1 1-乙基异喹啉 | CAS号126921-48-0 1-(2-piperidin-... | CAS号4965-09-7 1-甲基-1,2,3,4-四氢异喹啉

4-溴异喹啉置于吡啶,硫酸,双氧水,乙酸酐,Copper(II) Sulfate,溶剂黄146体系中,用 二氯甲烷 用作溶剂,化学反应 133.0H,反应生成1-甲基异喹啉
参考文献:异喹啉-1-羧甲醛硫代半脲的4和5取代衍生物的合成及其抗肿瘤活性.
标题:异喹啉-1-羧甲醛硫代半脲的4和5取代衍生物的合成及其抗肿瘤活性.
摘要:已经合成了各种取代的异喹啉-1-甲醛硫代半脲酮(12种化合物),并评估了患有l1210白血病的小鼠的抗肿瘤活性.4-溴-1-甲基异喹啉(4)与氢氧化铵,甲胺,乙胺和n-乙酰基乙二胺缩合得到相应的4-氨基,4-甲基氨基,4-乙基氨基和4-N-(乙酰乙基)氨基衍生物,然后将其转化为酰胺,然后氧化为醛,然后与硫代氨基甲酰肼缩合,生成硫代半氨基甲酮8A-C,9A-C和16.硝化4,然后用二氧化硒氧化,生成醛18,然后将其转化为醛18环状乙烯缩醛19.用吗啉将19缩合,然后催化还原硝基,并用硫代氨基脲处理,得到5-氨基-4-吗啉代异喹啉-1-羧甲醛硫代氨基脲(22).N-氧化1,5-二甲基异喹啉,然后用乙酸酐重排,酸水解后得到1,5-二甲基-4-羟基异喹啉,将其转化为乙酸盐,然后氧化得到4-乙酰氧基-5-甲基异喹啉-1-甲醛(32).磺化1,4-二甲基异喹啉,然后与氢氧化钾反应,乙酰化和氧化,得到5
Doi:10.1021/jm00021A012

专利信息

专利号:US-9755163-B2
优先权日:2010-04-30
标 题:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof
发明人：LI JIAN; TURNER ERIC
权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV; ARIZONA BOARD OF REGENTS ACTING FOR OR ON BEHALF OF ARIZONA STATE UNIV
摘要:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.

专利号:US-9324957-B2
优先权日:2010-04-30
标 题:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof
发明人：LI JIAN; TUMER ERIC
权利人:LI JIAN; TUMER ERIC; UNIV ARIZONA STATE
摘要:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof.

专利号:WO-2014004985-A1
优先权日:2012-06-29
标题 :1,4-azaborine compounds and methods of synthesis
发明人：LIU SHIH-YUAN; XU SENMIAO; KWONG RAYMOND C
权利人:STATE OF OREGON ACTING BY & THROUGH THE ST BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF; UNIV DISPLAY CORP
摘要:A compound comprising a structure of formula A

专利号:US-9698359-B2
优先权日:2011-05-26
标 题 :Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays
发明人：LI JIAN; TURNER ERIC
权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV
摘要:Platinum and palladium complexes are disclosed that can be useful as narrow band phosphorescent emitters. Also disclosed are methods for preparing and using the platinum and palladium complexes.

专利号:US-11739359-B2
优先权日:2020-05-01
标 题:Universal template strands for enzymatic polynucleotide synthesis
发明人：NGUYEN BICHLIEN; SMITH JAKE; CARLSON ROBERT; STRAUSS KARIN
权利人:MICROSOFT TECHNOLOGY LICENSING LLC
摘要:A universal template strand built with universal base analogs is used as a template for polynucleotide synthesis. The universal template strand can hybridize to any sequence of nucleotides. A new polynucleotide is synthesized by using a polymerase to extend a primer hybridized to the universal template strand. Unlike primer extension in polymerase chain reactions, base pairing with nucleotides in the template strand does not specify the sequence of the new polynucleotide. Instead, the sequence of the new polynucleotide is specified by the order of addition of protected nucleotides. After addition of a single species of protected nucleotide, the blocking group is removed and another protected nucleotide is added. The order of nucleotide addition can be varied to create any sequence. After synthesis, the polynucleotide can be dehybridized from the universal template strand. The universal template strand may then be reused to synthesize a different polynucleotide.

专利号:US-6084097-A
优先权日:1997-10-20
标题:Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
发明人：SINHA NEELIMA; JAIN SANJAY; SAXENA ANIL KUMAR; ANAND NITYA; SAXENA RAM MOHAN; DUBEY MANGAL PRASAD; RAY MADHUR; PATNAIK GYANENDRA KUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The invention relates to a process for the synthesis of 1-[4-Arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes used as potential therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders, having general formula 1 ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; a process of preparing said compounds and a method of treating hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders.