CAS: 6482-26-4; Methyl 2,2-Dibromoacetate

该化合物是一种有机化合物,其特征是其由乙酸和2,2-二溴替代物衍生的酯性功能组,其特性为:该化合物一般是一种无色黄色的黄色液体,有明显的醋味,具有明显的醋酸味;由于该酯组的存在,该化合物在有机溶剂中可溶解,且在水中表现出中等溶解性;二溴分成分有助于其再活性,使其在有机合成中成为潜在的中间体,并在各种化学反应中成为有用的试剂;这种化合物的乙酸衍生物经常用于生产药品,农用化学品和其他精美化学品;安全考虑十分重要,因为如果吸入或摄入,可能会对健康造成危害;应当采取适当的处理措施,以尽量减少接触.

英文名称Methyl 2,2-Dibromoacetate
中文名称2,2-二溴乙酸甲酯
IUPAC名称methyl 2,2-dibromoacetate
其它别名Methyl Dibromoacetate, 50Mg, Neat; Methyl Dibromoacetate Solution; 2,2-Dibromoacetic Acid Methyl Ester; Methyl 2,2-Dibromoacetate; Methyl Dibromoacetate@20 μg/ml In Mtbe; Acetic Acid, 2,2-Dibromo-, Methyl Ester; Lornoxicam Impurity Sm3-2
CAS编号6482-26-4
MFCD编号:MFCD00152631
EINECS号:623-724-4
分子式:C3H4Br2O2分子量:231.87
产品CID: 1631476
产品分类有机原料→分子砌块→脂肪链类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: DZFMIUJZSYIMPH-UHFFFAOYSA-N
InChI=1S/C3H4Br2O2/c1-7-3(6)2(4)5/h2H,1H3
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数1.0

相似化合物

20047-41-0 5445-17-0 617-33-4

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别急性毒性类别4(经口)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
严重眼刺激类别2A
易燃液体类别4
警示词Warning(警告)
危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H227 |可燃液体
防范说明P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P370+P378-P403+P233-P403+P235-P405-P501
UN编号UN 2398 3/PG 2
危险品标志F,Xi,Xn
安全声明16-26-36-24-9
危险类别码36/37/38-40-22-38-11
WGK Germany1

欧盟法规

ECHA物质C&L通报

上下游产品

合成工艺路线路线简述

📜重氮乙酸甲酯置于溴体系中,用二氯甲烷作为反应溶剂,以100%的收率获得产物二溴乙酸甲酯
参考文献:第二代全合成(-)-前异色酮d
标题:第二代全合成(-)-前异色酮d
摘要:达到了立体选择性,高收率的甲基甲硅烷基乙烯酮缩醛在多克级的基于苯醌的底物上的添加.引入的共轭物加成缩短了(-)-前异色酮d的总合成,并为进一步研究前异色酮e和f的总合成奠定了坚实的基础.
DOI:10.1002/ejoc.202000465

海关参考信息

2912110000-甲醛
2912120000-乙醛
2915110000-甲酸
2915211900-乙酸
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9242998-B2
优先权日:2013-02-07
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：HE SHUWEN; DAI XING; PALANI ANANDAN; NARGUND RAVI; LAI ZHONG; ZORN NICOLAS; XIAO DONG; DANG QUN; MCCOMAS CASEY C; LI PENG; PENG XUANJIA; SOLL RICHARD
权利人:HE SHUWEN; DAI XING; PALANI ANANDAN; NARGUND RAVI; LAI ZHONG; ZORN NICOLAS; XIAO DONG; DANG QUN; MCCOMAS CASEY C; LI PENG; PENG XUANJIA; SOLL RICHARD; MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9265773-B2
优先权日:2011-09-08
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI; MERCK SHARP & DOHME; MSD ITALIA SRL
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.