CAS: 645-15-8; Bis(4-Nitrophenyl) Phosphate

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CAS号3871-20-3 三(4-硝基苯基)磷酸酯 | CAS号100-02-7 对硝基苯酚 | CAS号838-85-7 磷酸二苯酯 | CAS号2015-56-7 氨基磷酸二苯酯 | CAS号7697-37-2 硝酸 | CAS号100-02-7 对硝基苯酚 | CAS号330-13-2 磷酸单-(4-硝基-苯酚)酯 | CAS号14609-74-6 Phenol, 4-nitro... | CAS号824-78-2 4-硝基苯酚钠 | CAS号6546-97-0 1-[chloro-(4-ni... | CAS号15930-83-3 Methyl 4-nitrop... | CAS号42893-52-7 butyl methyl (4... | CAS号52625-61-3 Tetrakis(4-(hyd...

磷酸二苯酯置于硝酸体系中,化学反应生成 双(对硝基苯基)磷酸酯
参考文献:Hoeflake,Recueil Des Travaux Chimiques Des Pays-Bas,1917,Vol. 36,P. 51,57,62
标题:Hoeflake,Recueil Des Travaux Chimiques Des Pays-Bas,1917,Vol. 36,P. 51,57,62

专利信息

专利号:US-4041111-A
优先权日:1975-03-04
标题:Phosphonate monoesters and method of preparation
发明人：KELLY SUSAN J; BUTLER LARRY G
权利人:PURDUE RESEARCH FOUNDATION
摘要:Synthesis of phosphonate monoesters, as well as the use of such monoesters as substrates for enzymes which normally hydrolyze phosphodiester linkages, and a method for distinguishing between Type I and Type II phosphodiesterase enzymes using such monoesters as substrates are disclosed herein. Monoesters of phosphonic acids are prepared by the displacement of chloride from an appropriate phosphonic acid dichloride by a phenol or alcohol with pyridine as the solvent, reacting the same and then removing the solvent, after which the remaining ester chloride and dichloride are hydrolyzed by addition of water. The acid and ester are then separated and the acid-free ester is taken up in a polar organic solvent and precipitated as a salt by the addition of aqueous base, with the product then being filtered, washed with fresh acetone, dried and then stored until needed. The thus formed phosphonate monoesters are shown to be effective for use as substrate for phosphodiesterase of the Type I specificity and are shown to be ineffective for use as substrates for phosphodiesterase of the Type II specificity. The type of phosphodiesterase is therefore determined by the amount of activity against phosphonate monoesters.

专利号:US-9963735-B2
优先权日:2007-08-17
标题 :Selective 5′ ligation tagging of RNA
发明人：JENDRISAK JEROME; DAHL GARY A; VAIDYANATHAN RAMESH
权利人:EPICENTRE TECH CORPORATION
摘要:The present invention provides novel compositions, kits and methods employing RNA 5′ polyphosphatases, RNA 5′ monophosphatases, capping enzymes, decapping enzymes, nucleic acid pyrophosphatases and RNA ligases, as well as other enzymes, for selective 5′ ligation tagging of desired classes of RNA molecules that differ with respect to particular chemical moieties on their 5′ ends. The 5′ tagged RNA molecules can be used for synthesis of tagged first-stand cDNA, double-stranded cDNA, and sense or antisense RNA for a variety of uses.

专利号:WO-0110870-A1
优先权日:1999-08-10
标题:Transition metal complexes of n,n',n'-trialkyl- cis,cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use
发明人：BRECHBIEL MARTIN; PLANALP ROY P; DEAL KIM
权利人:US HEALTH; BRECHBIEL MARTIN; PLANALP ROY P; DEAL KIM
摘要:The present invention provides transition metal complexes of N,N',N'-trialkyl-cis,cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use in vitro and in vivo, such as a therapeutic agent or a delivery/imaging agent.

专利号:US-6765104-B1
优先权日:1999-08-10
标题 :Transition metal complexes of n, n',n″trialkyl-cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use
发明人：BRECHBIEL MARTIN; PLANALP ROY P; DEAL KIM
权利人:US HEALTH
摘要:The present invention provides transition metal complexes of N,N′,N″-trialkyl-cis,cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use in vitro and in vivo, such as a therapeutic agent or a delivery/imaging agent.

专利号:US-6022500-A
优先权日:1995-09-27
标 题:Polymer encapsulation and polymer microsphere composites
发明人：JOHN VIJAY T; MCPHERSON GARY L; AKKARA JOSEPH A; KAPLAN DAVID L
权利人:US ARMY
摘要:A process is described for the enzyme catalyzed synthesis of polymeric microspheres from monomers such as ethylphenol, naphthols and hydroxypyrenes in reverse micelles in the presence of a detergent. Polymeric microspheres synthesized are porous with nonuniform densities. Polymers prepared from naphthols and hydroxypyrenes are fluorescent with electroluminescent properties. A number of materials such as enzymes, drugs and inorganic materials such as iron oxide and cadmium sulfide are encapsulated in the hollow polymeric microspheres synthesized. These encapsulations are carried out during or after the syntheses of the polymeric microspheres. Functional properties of the encapsulated materials such as enzyme, magnetic and nonlinear optical properties are demonstrated in the polymeric composites.

专利号:RU-2111967-C1
优先权日:1996-09-26
标题:Method of synthesis of aciclovir