CAS: 5832-44-0; 4-Methyl-3-Nitropyridine

相似化合物

3430-27-1 1074-99-3 153813-70-8

上下游产品

malonic acid dibenzyl ester 4-chloro-3-nitropyridine 3-nitropyridine chloroacetic acid ethyl ester 3-nitro-4-[(E)-2-phenylethenyl]pyridine 3-amino-4-methylpyridine 3-nitro-4-pyridinecarboxaldehyde 3-nitropyridine-4-carboxylic acid

4-甲基吡啶置于硝酸,三氟乙酸酐,Sodium Disulfite体系中,化学反应 34.0H,以86%的收率获得产物3-硝基-4-甲基吡啶
参考文献:通过用硝酸硝化吡啶来制备硝基吡啶.
标题:通过用硝酸硝化吡啶来制备硝基吡啶.
摘要:在三氟乙酸酐中用硝酸硝化吡啶1A-O,得到相应的3-硝基吡啶6A-N,产率为10-83%.
DOI:10.1039/b413285H

专利信息

专利号:US-7060818-B2
优先权日:2003-02-21
标题:Synthesis of macrocyclic tetraamido compounds and new metal insertion process
发明人：HORWITZ COLIN P; GHOSH ANINDYA
权利人:UNIV CARNEGIE MELLON
摘要:An improved method of synthesizing a macrocyclic tetraamido compound includes protecting the amino portion of an amino carboxylic acid to form a protected amino carboxylic acid; exposing the protected amino carboxylic acid to a first solvent, preferably a hydrocarbon solvent, such as toluene or 1,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane. The carboxylic acid portion of the protected amino carboxylic acid is then converted to an activated carboxylic acid by one of esterification or acid halide formation, to form a protected amino activated carboxylic acid derivative. The protected amino activated carboxylic acid derivative is reacted with a diamine in the presence of a second solvent, such as THF or ,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane, to form a protected diamide diamine intermediate. Following deprotection, the diamide diamine intermediate is reacted with an activated diacid, such as an activated malonate, oxalate or succinate derivative to form the macrocyclic tetraamido compound. The macrocyclic tetraamido compound may further be complexed with a transition metal.

专利号:US-2004167329-A1
优先权日:2003-02-21
标 题:Synthesis of macrocyclic tetraamido compounds and new metal insertion process

专利号:WO-2004076425-A1
优先权日:2003-02-21
标题:Improved synthesis of macrocyclic tetraamido compounds and new metal insertion process