📜四甲基哌啶酮置于盐酸体系中,用 异丙醇 用作溶剂,以64%的收率获得2,2,6,6-四甲基哌啶酮盐酸盐 参考文献:Processes For Making Modulators Of Cystic Fibrosis Transmembrane Conductance Regulator 标题:Processes For Making Modulators Of Cystic Fibrosis Transmembrane Conductance Regulator 摘要:该披露提供了制备化合物式(i)的过程.
专利号:US-10807954-B2 优先权日:2018-12-07 标 题:Method for preparing triacetone amine 发明人:MINKE KATHARINA; RIEB JULIA; NEUMANN MANFRED 权利人:EVONIK OPERATIONS GMBH 摘要:An improved method is used for preparing triacetone amine while recycling the by-products. This involves treating the crude product from triacetone amine preparation, which leads to an increase in the content of compounds which react readily with ammonia. This method enables efficient recycling of the by-products formed in the synthesis of triacetone amine.
专利号:US-11731940-B2 优先权日:2020-05-07 标 题:Process for preparing triacetonamine 发明人:MINKE KATHARINA; GRASKAMP HOLGER 权利人:EVONIK OPERATIONS GMBH 摘要:An improved process can be used for preparing triacetonamine. The process involves performing an absorption step in which acetone present in the crude product is removed from triacetonamine by distillation, and in gaseous form is then absorbed in countercurrent into fresh, liquid acetone. The acetone stream thus obtained is then converted further to triacetonamine. This process enables more energy-efficient reutilization of the unreacted reactants used in the synthesis of triacetonamine, and thus lowers overall both the use of reactants and the energy expenditure.
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