CAS: 25488-59-9; (3R,4R)-3,4-Bis(3,4-Dimethoxybenzyl)Dihydrofuran-2(3H)-One
- 英文名称(3R,4R)-3,4-Bis(3,4-Dimethoxybenzyl)Dihydrofuran-2(3H)-One
- 中文名称甲基牛蒡酚; 甲基牛蒡子素
- IUPAC名称(3R,4R)-3,4-bis(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-one
- 其它别名Maculatin; Dimethylmatairesinol; Dimethoxybenzyl)Butyrolactone2,3-Bis(3,4-; 2,3-Bisbutyrolactone; (3R)-3α,4β-Bis(3,4-Dimethoxybenzyl)-4,5-Dihydrofuran-2(3H)-One; (3R)-3α,4β-Bis(3,4-Dimethoxybenzyl)Dihydrofuran-2(3H)-One; (3R,4R)-3,4-Bis(3,4-Dimethoxybenzyl)Tetrahydrofuran-2-One; Arctigenin Methyl Ether
- CAS编号25488-59-9
- MFCD编号:MFCD00800709
- FDA UNII编号:9TF8GZN966
- 分子式:C22H26O6分子量:386.44
- 产品CID: 1215648
- 同类组份化合物CAS25488-59-9 (methyl ether)26788-57-8 (mustard)7770-78-7 (parent)
- 产品分类天然产物 → 木脂素
物理性质
- 熔点125-127 °C
- 沸点545.6±45.0 °C(预测)
- 闪点237.2 °C
- 密度1.175±0.06 g/cm3(预测)
- PSA:63.22
- LogP:3.2954
- 折射率1.552
- 蒸汽压5.82E-12 mmHg at 25 °C
- 溶解性Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- 外观形态粉末
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用该化合物是亚斯特罗塞亚州某些植物中发现的离子体,包括大(ACCTIUM LAPA)和(SAUSSUREA HTEROMALLA),它显示了体外抗病毒和抗癌效应,是弧丁的腺.在日本脑炎的鼠标模型中,使用丙基GENIN已经证明有效.
上下游产品
g-threo-2,3-diveratryl-succinic acid-anhydrideDg-threo-2,3-diveratryl-succinic acid-anhydride g-threo-2,3-diveratryl-succinic acid-anhydrideLg-threo-2,3-diveratryl-succinic acid-anhydride 4-bromomethyl-1,2-dimethoxybenzene (R)-4-(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-onefuran-1(3H)-one9-(3,4-Dimethoxyphenyl)-6,7-dimethoxynaphtho2,3-cfuran-1(3H)-one dehydrodimethylconidendrin g-threo-2,3-bis-(3,4-dimethoxy-benzyl)-4-hydroxy-butyric acidLg-threo-2,3-bis-(3,4-dimethoxy-benzyl)-4-hydroxy-butyric acid 24H34O6C24H34O6合成工艺路线路线简述
📜((3,4-Dimethoxyphenyl)Methylene)Bis(Phenylsulfane)置于氢氧化钾,Sodium Tetrahydroborate,正丁基锂,地昔帕明,Nickel Dichloride体系中,用 甲醇,乙醇 用作溶剂,化学反应 13.67H,反应生成甲基牛蒡酚; 甲基牛蒡子素
参考文献:Pelter,Andrew; Ward,Robert S.; Jones,Martin D.,Journal Of The Chemical Society. Perkin Transactions I,1993,# 21,P. 2631-2638
标题:Pelter,Andrew; Ward,Robert S.; Jones,Martin D.,Journal Of The Chemical Society. Perkin Transactions I,1993,# 21,P. 2631-2638
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2907210001-间苯二酚
2909110000-乙醚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Shi X, Sun H, Zhou D, Xi H, Shan L. Arctigenin Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats. Inflammation. 2014 Jul 10. [Epub ahead of print]
合成参考文献
参考文献:10.1002/chin.200340213
摘要:Adesina SK, Adebayo AS, Adesina SKO, Groening R. New Constituents of Piper guineense Fruit and Leaf. ChemInform. 2003 Sep 15;34(40). doi: 10.1002/chin.200340213.
参考文献:10.1016/0031-9422(95)00464-i
摘要:Vidigal MCS, Cavalheiro AJ, Kato MJ, Yoshida M. Lignans from kernels of Virola michelii Heckel. Phytochemistry. 1995 Nov;40(4):1259–61. doi: 10.1016/0031-9422(95)00464-i.
参考文献:10.1016/s0040-4020(01)90430-2
摘要:Estévez-Braun A, Estévez-Reyes R, G. González A. Structural elucidation and conformational analysis of new lignan butenolides from the leaves of bupleurum salicifolium. Tetrahedron. 1994 Apr;50(17):5203–10. doi: 10.1016/s0040-4020(01)90430-2.
参考文献:10.1016/s0040-4039(01)88517-8
摘要:Reisch J, Szendrei K, Novák I, Minker E, Pàpay V. Inhaltsstoffe der blüten von ptelea trifoliata: Arctigenin-methyläther, (+)-hydroxylunin und ptelefolin. Tetrahedron Letters. 1969 Jan;10(43):3803–6. doi: 10.1016/s0040-4039(01)88517-8.
参考文献:10.1021/np030125s.s001
摘要:Antineoplastic Agents 522. Hernandia peltata (Malaysia) and Hernandia nymphaeifolia (Republic of Maldives). (). doi: 10.1021/np030125s.s001.
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