CAS: 2150-48-3; 3,6-Bis(Diethylamino)Xanthylium Chloride

该化合物是一种属于Xanthene染色类的合成染料,其特点是红色至粉色,具有活力,在各种应用中有用,包括生物污点和pH指标.Pyronine B在水和有机溶剂中表现出溶解性,这增强了其在实验室环境中的效用.该化合物经常用于染色核糖酸特别是RNA的生理学和细胞学中,因为它与这些生物分子的亲近性.其荧光特性允许在特定光条件下进行可视化,使其在显微镜中具有价值.此外,Pyronine B已经研究其在生物化学和分子生物学领域的潜在应用.然而,像许多合成染料一样,它应该谨慎处理,因为如果染色或接触皮肤,它可能会对健康造成风险.在实验室环境中与该物质打交道时,应该遵循适当的安全议定书.

结构式图片

上下游产品

CAS号6274-83-5 5-diethylamino-... | CAS号7647-01-0 盐酸 | CAS号64-18-6 甲酸 | CAS号56-81-5 甘油 | CAS号91-68-9 3-羟基-N,N-二乙基苯胺

合成工艺路线路线简述

    📜2,2'-亚甲基二[5-(二乙基氨基)苯酚]置于硫酸,Sodium Hydroxide,盐酸,Sodium Nitrite体系中,用 水 用作溶剂,以56%的收率获得派洛宁b
    参考文献: 3,6-Disubstituted Xanthylium Salts[fr] Sels De Xanthylium Disubstitués En 3 Et 6
    标题: 3,6-Disubstituted Xanthylium Salts[fr] Sels De Xanthylium Disubstitués En 3 Et 6

    海关参考信息

    专利信息


    专利号:US-2018312534-A1
    优先权日:2015-10-16
    标题:Fluorescent anticancer platinum drugs
    发明人:SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
    权利人:INVICTUS ONCOLOGY PVT LTD
    摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

    专利号:US-2023097824-A1
    优先权日:2020-05-08
    标 题:Semi-synthesis and use of racemic hematoxylin
    发明人:DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR
    权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC
    摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.

    专利号:US-7888116-B2
    优先权日:2004-07-22
    标 题 :Uses of notch receptors, notch ligands, and notch modulators in methods related to metabolic diseases
    发明人:EGAN JOSEPHINE M; DOYLE MAIRE E
    权利人:US HEALTH
    摘要:Disclosed are methods for identifying and isolating a precursor cell. Also, disclosed are methods of increasing insulin synthesis from a pancreatic B-cell. Further, disclosed are methods of improving pancreatic B-cell function. Still further, disclosed are methods of preventing or delaying the onset of a metabolic disease, methods of treating or preventing a metabolic disease in a subject, and to compositions for treating or preventing a metabolic disease in a subject in need of such treatment or prevention.

    专利号:US-2005202459-A1
    优先权日:2003-09-23
    标 题 :Intercalation-mediated synthesis of polymers

    专利号:US-9408848-B2
    优先权日:2008-08-15
    标 题 :Fluorescent CDK inhibitors for treatment of cancer
    发明人:YENUGONDA VENKATA MAHIDHAR; BROWN MILTON L
    权利人:YENUGONDA VENKATA MAHIDHAR; BROWN MILTON L; UNIV GEORGETOWN
    摘要:Disclosed are molecules and their synthesis. The fluorescent moiety also facilitates screening, tracking, and pharmacodynamic studies of the drug in a biological system both in vitro and in vivo.

    专利号:US-7368560-B2
    优先权日:2003-09-23
    标题:Intercalation-mediated synthesis of polymers
    发明人:HUD NICHOLAS V
    权利人:GEORGIA TECH RES INST
    摘要:Methods and compositions for synthesizing biopolymers using an intercalator are provided. Aspects provide compositions and methods for synthesizing biopolymers with non-natural backbones or non-natural biopolymer subunits using natural biopolymer templates. Other aspects provide compositions and methods for synthesizing biopolymers using a template with a non-natural backbone on non-natural biopolymer subunits.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Zhang XF, Zhang J, Lu X. The Fluorescence Properties of Three Rhodamine Dye Analogues: Acridine Red, Pyronin Y and Pyronin B. J Fluoresc. 2015 Jul;25(4):1151-8. doi: 10.1007/s10895-015-1610-5. Epub 2015 Jul 11. doi: 10.1016/j.saa.2014.12.010. Epub 2014 Dec 16. doi: 10.1128/JVI.00839-14. Epub 2014 Aug 6.
    4: Chen WX, Zhu HL, Xue M, Zhou H, Zhao F, Yan N, Chen Y. Quick staining technique for myeloperoxidase using potassium iodide and oxidized pyronine B. Acta Histochem. 2014 Jan;116(1):292-6. doi: 10.1016/j.acthis.2013.08.001. Epub 2013 Sep 14. doi: 10.1016/j.foodchem.2013.01.087. Epub 2013 Feb 8. doi: 10.1016/j.saa.2012.09.098. Epub 2012 Oct 12. doi: 10.1016/j.aca.2011.07.026. Epub 2011 Jul 23. doi: 10.1016/j.talanta.2011.06.053. Epub 2011 Jun 24. doi: 10.1039/c0dt01534b. Epub 2011 Mar 3. doi: 10.1002/cphc.200800776. doi: 10.1016/j.jcis.2008.12.058. Epub 2008 Dec 25. doi: 10.1093/jac/dkn407. Epub 2008 Sep 26. Chinese. Epub 2006 May 10.

    合成参考文献


    摘要:National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program., JAN1986
    摘要:F, E. Ray and M. L. Jung. Brit. J. Cancer 5, 358 (1951).
    参考文献:10.1038/s41467-021-24855-6
    摘要:Miao Y, Qian N, Shi L, Hu F, Min W. 9-Cyanopyronin probe palette for super-multiplexed vibrational imaging. Nature Communications. 2021 Jul 26;12(1):4518. doi: 10.1038/s41467-021-24855-6.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知