2,6-二甲基吡啶置于硫酸,硝酸体系中,用90%的收率获得2,6-二甲基-3-硝基吡啶 参考文献:Oxidative Demethylation Of Some Methylnitropyridine 1-Oxides 标题:Oxidative Demethylation Of Some Methylnitropyridine 1-Oxides 摘要: Doi:10.1016/s0040-4039(00)93168-X
专利号:US-5869676-A 优先权日:1997-05-15 标题:Process for the synthesis of ribonucleotide reductase inhibitors 3-AP and 3-AMP 发明人:NIU CHUANSHENG; LI JUN; LI XIUYAN; DOYLE TERRENCE W; CHEN SHU-HUI 权利人:VION PHARMACEUTICALS INC 摘要:The present invention relates to improved, efficient chemical syntheses of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and 3-amino-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-AMP).
专利号:RU-2198875-C2 优先权日:1997-05-15 标 题:Methods of synthesis of pyridine-2-carboxaldehyde thiosemicarbazones and intermediate pyridine-2-carboxaldehydes
专利号:EP-0984932-A4 优先权日:1997-05-15 标题:METHOD FOR THE SYNTHESIS OF THE RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP
专利号:WO-9851670-A1 优先权日:1997-05-15 标 题:Process for the synthesis of ribonucleotide reductase inhibitors 3-ap and 3-amp
专利号:EP-0984932-A1 优先权日:1997-05-15 标 题 :Process for the synthesis of ribonucleotide reductase inhibitors 3-ap and 3-amp
专利号:AU-728165-B2 优先权日:1997-05-15 标题 :Process for the synthesis of ribonucleotide reductase inhibitors 3-AP and 3-AMP
摘要:Mérour, J.-Y.; Joseph, B., Science of Synthesis Knowledge Updates, (2016) 3, 118. 摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 2004. Toxicity, Repellency of Phytotoxicity of 979 Chemicals to Birds, Mammals and Plants. Research Report No. 04-01. National Wildlife Research Center, Fort Collins, Colorado. 118 pp. 摘要:C.D. Johnson, A.R. Katritzky, B.J. Ridgewell and M. Viney. J. Chem. Soc., B 1967, 1204.