CAS: 14036-06-7; Diethoxymethyl Acetate

相似化合物

628-51-3 4382-76-7 70767-92-9

上下游产品

CAS号108-24-7 乙酸酐 | CAS号122-51-0 原甲酸三乙酯 | CAS号64-19-7 冰醋酸 | CAS号110089-43-5 ethyl N-(5-brom... | CAS号3788-94-1 2-乙氧亚甲基乙酰乙酸乙酯 | CAS号41078-02-8 恩丙茶碱 | CAS号1500-89-6 Methanimidic ac... | CAS号905-96-4 3,3'-二乙基氧杂羰花青碘 | CAS号17997-33-0 (二乙氧基甲基)膦酸二乙酯 | CAS号18232-30-9 2-庚炔乙酸二乙酯 | CAS号886-65-7 1,4-二苯基1,3-丁二烯 | CAS号25226-98-6 Cinnamaldehyde ... | CAS号81149-95-3 cis-cinnamaldeh...

📜乙酸酐,原甲酸三乙酯置于甲酸体系中,化学反应 24.0H,以66%的收率获得乙酸二乙氧基甲酯
参考文献:有机金属试剂取代二烷氧基甲基乙酸酯的乙酰氧基:通向烯丙基,炔丙基,高烯丙基,高炔丙基和α-锡烷基缩醛的途径
标题:有机金属试剂取代二烷氧基甲基乙酸酯的乙酰氧基:通向烯丙基,炔丙基,高烯丙基,高炔丙基和α-锡烷基缩醛的途径
摘要:为了寻找制备功能性乙缩醛的新方法,研发了用有机金属试剂取代二烷氧基甲基乙酸酯的乙酰氧基.乙酰氧基的取代效率高度依赖于有机金属试剂的性质:具有抗衡离子的强亲电助剂的柔软亲核试剂是最好的试剂.通过这种途径制备了烯丙基,炔丙基,高烯丙基,高炔丙基和α-锡烷基缩醛,其中二烷氧基甲基乙酸酯经常用作二烷基苯基原甲酸酯的有用替代物.
Doi:10.1016/0022-328X(92)83085-V

专利信息

专利号:EP-0310950-B1
优先权日:1983-11-18
标题 :Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes
摘要:Compounds of the types (I) and (II) are disclosed, wherein each R5 is independently selected from the group consisting of alkyl of one to about four carbon atoms, alkoxy of one to about four carbon atoms and halogen, and n is an integer from 0 to 2, with the proviso that if n is 2, then said R5 substituents together contain no more than 6 carbon atoms; R6 is selected from the group consisting of hydroxyalkyl of one to about six carbon atoms and cyclohexylmethyl; and R7 is selected from the group consisting of alkyl of one to about four carbon atoms and hydrogen. These compounds may be used as intermediates for the synthesis of 1H-imidazo[4,5-c]quinoline derivatives.

专利号:US-3558614-A
优先权日:1967-09-05
标题:Synthesis of tetranuclear dyes
发明人：JENKINS PHILIP W
权利人:EASTMAN KODAK CO
摘要:TETRANUCLEAR DYES DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE AND A 2-IMIDAZOLIN-4-SELENONE ARE PREPARED IN GOOD YIELDS BY CONDENSING A QUATERNIZED MEROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE OR A 2-IMIDAZOLIN4-SELENONE WITH (1) A DIALKOXYALKYL ESTER OF AN ORGANIC ACID, (2) A TRIALKOXY ALKANE OR ARYL COMPOUND, (3) A 3,3-DIALKOZY-1ALKOXYPROPENE, (4) A 1-ANILINO-5-PHENYLIMINO-1,3-PENTADIENE OR (5) A SECOND QUATERNIZED MROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4THIONE OR A 2-IMIDAZOLIN-4-SELENONE, EACH HAVING SUBSTITUTED ON THE CARBON IN THE 2-POSITION A GROUP SUCH AS A B-ACETANILIDOVINYL GROUP, A 4-ACETANILIDO-1,3-BUTADIENYL GROUP, AND A 6-ACETANILIDO-1,3,5-HEXADIENYL GROUP.

专利号:US-5688933-A
优先权日:1989-10-16
标题 :Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo 2.2.1!hept-5-en-one
发明人：EVANS CHRISTOPHER THOMAS; ROBERTS STANLEY MICAHEL
权利人:CHIROSCIENCE LTD
摘要:Lactams of 1-amino-3-carboxylic acid cyclic compounds are provided in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic lactam with a novel lactamase. The products are useful in the synthesis of chiral carbocyclic nucleotides. The enantiomer is preferably 2-azabicyclo 2.2.1!hept-5-en-3-one.

专利号:US-4216319-A
优先权日:1976-06-09
标题:Synthesis of 2,4-diamino-5-benzylpyrimidines using benzyl cyanoacetal intermediates
发明人：SWARINGEN ROY A JR; YEOWELL DAVID A
权利人:BURROUGHS WELLCOME CO
摘要:Benzyl cyanoacetals of formula: ##STR1## wherein R 1 , R 2 and R 3 are the same or different and each is a halogen or a hydrogen atom, an alkoxy group, an alkyl group, or a dialkylamino group; R 4 is an alkoxycarbonyl group, or an aldehyde group; and R 5 is an alkyl group; the alkyl or alkoxy groups each having from 1 to 4 carbon atoms, and their use as intermediates in the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines. They are prepared from a reaction between an orthoester and an α-substituted-β-benzylpropionitrile and then the resulting cyanoacetal is converted to the benzylpyrimidine by reaction with guanidine.

专利号:WO-2017222946-A1
优先权日:2016-06-20
标题 :Adenylyl cyclase inhibitors, pharmaceutical compositions and methods of use thereof
发明人：LEVY DANIEL E; ABARZUA PATRICIO; VATNER DOROTHY E; VATNER STEPHEN
权利人:VASADE BIOSCIENCES
摘要:Disclosed are inhibitors of adenylyl cyclase of Formula (I) having variables as described, as well as methods of synthesis thereof, pharmaceutical compositions thereof, and methods of treatment of various diseases using the pharmaceutical compositions.

专利号:US-5126347-A
优先权日:1989-02-13
标 题 :Isomeric dideoxynuclesides
发明人：HURYN DONNA M; TAM STEVE YIK-KAI; WEIGELE MANFRED
权利人:HOFFMANN LA ROCHE
摘要:Isomeric derivatives of 2',3'-dideoxyadenosine and 2',3'-dideoxyguanosine wherein the adenine or guanine base is attached to the 1' position of the iso-dideoxysugar residue by the 9-N position, the novel intermediates used in the synthesis of these compounds, and a method for treating a subject infected with a retrovirus by administering the compounds of the invention.