CAS: 1075705-01-9; 4-Fluoro-2-Methoxy-5-Nitroaniline

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1802924-13-5 1865729-77-6 1850312-96-7

上下游产品

4-fluoro-2-methoxyaniline 4-fluoro-2-methoxy-1-nitrobenzene sodium methylate 5-amino-2,4-difluoronitrobenzene 5-fluoro-2-methanesulfonylamino-4-nitroanisole 5-fluoro-2-(2,3-difluoro-6-methoxybenzylamino)-4-nitroanisole

5-氟-2-硝基苯酚置于硫酸,Palladium 10% On Activated Carbon,氢气,硝酸,Potassium Carbonate体系中,用 甲醇,二氯甲烷,丙酮 用作溶剂,化学反应 75.0H,反应生成4-氟-2-甲氧基-5-硝基苯胺
参考文献:代替抗癌剤の治療効果予測剤
标题:代替抗癌剤の治療効果予測剤
摘要:针对非小细胞肺癌细胞中出现的各种上皮生长因子受体基因突变导致耐药时,提供一种基因突变治疗效果预测剂,以选择对这种耐药具有有效性的替代抗癌药物,该替代抗癌药物是一种低侵袭性甚至非侵袭性的放射性标记替代抗癌药物,可进行影像诊断. 解决方案:替代抗癌药物的治疗效果预测剂是一种放射性同位素标记的药物,可选择用于药物耐性的替代抗癌药物,且最好是用放射性同位素标记的替代抗癌药物.替代抗癌药物的治疗效果预测剂是指抗癌药物和替代抗癌药物分别是上皮生长因子受体基因突变引起的药物耐性的上皮生长因子受体酪氨酸激酶抑制剂. 选择图:无

专利信息

专利号:US-11198684-B2
优先权日:2017-07-28
标 题 :Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same
发明人：OH SANG-HO; KHOO JA-HEOUK; LIM JONG-CHUL; LEE DOO-BYUNG; LEE JUNG-AE; LEE JUN-SUP; JU HYUN; SHIN WOO-SEOB; JEON SANG-SEOL
权利人:YUHAN CORP
摘要:The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.

专利号:CN-108187666-B
优先权日:2018-01-23
标 题:Preparation of biomass derived palladium catalyst and application of biomass derived palladium catalyst in synthesis of antitumor drug ocitinib

专利号:WO-2019022487-A1
优先权日:2017-07-28
标题 :INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR TO PROTEIN KINASE AND METHODS FOR THEIR PREPARATION

专利号:FI-3658547-T3
优先权日:2017-07-28
标题 :INTERMEDIATES USABLE IN THE SYNTHESIS OF A SELECTIVE INHIBITOR DIRECTED AGAINST PROTEIN KINASE AND METHODS FOR THEIR PREPARATION

专利号:CN-111032650-A
优先权日:2017-07-28
标题 :Novel intermediates that can be used in the synthesis of aminopyrimidine derivatives, methods for their preparation and methods for preparing aminopyrimidine derivatives using the same

专利号:US-2021155607-A1
优先权日:2017-07-28
标题:Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same