CAS: 78111-17-8; (R)-2-Hydroxy-3-((2S,5R,6R,8S)-5-Hydroxy-8-((R,E)-4-((2R,4A'R,5R,6'S,8'R,8A'S)-8'-Hydroxy-6'-((1S,3S)-1-Hydroxy-3-((2S,3R,6S)-3-Methyl-1,7-Dioxaspiro[5.5]Undecan-2-yl)Butyl)-7'-Methyleneoctahydro-3H,3'H-Spiro[furan-2,2'-Pyrano[3,2-B]Pyran]-5-yl)But-3-En-2-yl)-10-Methyl-1,7-Dioxaspiro[5.5]Undec-10-En-2-yl)-2-Methylpropanoic Acid

上下游产品

CAS号104307-13-3 tribenzyl okada... | CAS号194038-95-4 (((2R,3S)-1-((4... | CAS号194039-05-9 (S)-2-((2S,6R,8...

📜3-((2R,4Ar,6S,8R,8Ar)-8-(Benzyloxy)-6-((1S,3S)-1-(Benzyloxy)-3-((2S,3R,6S)-3-Methyl-1,7-Dioxaspiro[5.5]Undecan-2-yl)Butyl)-2-Methoxy-7-Methyleneoctahydropyrano[3,2-B]Pyran-2-yl)Propan-1-Ol置于lithium Hydroxide,Lidbb,Bh3 System,水,戴斯-马丁氧化剂,对甲苯磺酸,N,N-二异丙基乙胺,Lithium Chloride,(S)-2-甲基-Cbs-恶唑硼烷体系中,用 四氢呋喃,乙腈 作为反应溶剂,化学反应生成 黑海棉酸钠盐
参考文献:An Efficient Total Synthesis Of Okadaic Acid
标题:An Efficient Total Synthesis Of Okadaic Acid
摘要:
DOI:10.1021/ja9715206

专利信息

专利号:WO-2025062384-A2
优先权日:2023-09-23
标题 :A method for synthesis of metal halide perovskite (cspbbr3) nano/microcrystals
发明人：M A GOKUL; RAHMAN ATIKUR
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES PUNE IISER PUNE
摘要:The present invention relates to metal halide perovskite (CsPbBr3) nano/microcrystals. Specifically, the present invention relates to a method for the synthesis of metal halide perovskite (CsPbBr3) nano/microcrystals. The present invention uses an easy, scalable low temperature growth of metal halide nanoparticles like CsPbBr3. The method uses a clever play on the solubility and ion exchange mechanism to precipitate nano and microcrystals of metal halide perovskites. The synthesis resulted in stable perovskite crystals with high photo- luminescence, ultralow dark current and control over their morphology. The combination of ultralow dark current, high responsivity, exceptional detectivity, and broad-band photon detection capabilities makes these crystals an excellent choice for upcoming sensors and detector technologies.

专利号:WO-2024137710-A3
优先权日:2022-12-19
标 题 :Improved enzymes and methods for the synthesis of cannabinoids
发明人：KAMBOURAKIS SPIROS; KOMOR RUSSELL SCOTT; CAIAZZA NICKY CHRISTOPHER; KEUL NICHOLAS DONALD; WALKER CALEB MARSHALL
权利人:CELLIBRE INC
摘要:Disclosed herein are novel CBGA and CBGVA synthases and methods for improvement of their overall activities for the synthesis of CBGA and CBGVA from their respective precursors, olivetolic acid (OA) or divarinic acid (DVA) and GPP. Also disclosed are fusion proteins to enhance synthesis of CBGA and CBGVA. The methods described herein also increase the titer and the purity of CBGA and CBGVA made by a cell by 1) decreasing the formation of byproducts FCBGA and FCBGVA that are synthesized from the respective prenylation of OA and DVA with FPP, 2) increasing the intracellular availability of OA and DVA and 3) increasing the speed of CBGA and CBGVA formation, while reducing accumulation of intermediates.

专利号:US-12391691-B2
优先权日:2018-11-16
标题:Synthesis of key intermediate of KRAS G12C inhibitor compound
发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as

专利号:US-2025206736-A1
优先权日:2019-11-14
标题 :Synthesis of kras g12c inhibitor compound
发明人：CORBETT MICHAEL THOMAS; CAILLE SEBASTIEN
权利人:AMGEN INC
摘要:The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.

专利号:US-2025171686-A1
优先权日:2023-11-27
标题 :Room temperature ambient synthesis of metal-doped halide perovskite nanocrystals
发明人：FELDMANN SASCHA; WUTTIG MATEO CARDENES; VANORMAN ZACHARY
权利人:ECOLE POLYTECHNIQUE FED LAUSANNE EPFL; PRESIDENT AND FELLOWS OF HARVARD COLLEGE CAMBRIDGE MA
摘要:A method of preparing a composition including crystalline particles of a halide perovskite, a composition and a perovskite-based device including the same. The halide perovskite has a chemical formula ABX3, wherein A is a monocation, B is selected from a combination of lead (II) and a dopant and X is selected from a halide.

专利号:US-2025206743-A1
优先权日:2022-03-25
标 题:Tyk2 inhibitor synthesis and intermediates thereof
发明人：MASSE CRAIG E; PHADKE AVINASH S; LAWSON JON P; LEVY STUART; YANG XIAOWEI; WU GUISHENG; FAN SHUFENG
权利人:TAKEDA PHARMACEUTICALS CO
摘要:Described herein are methods of synthesis of a tyrosine-protein kinase 2 (TYK2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. Also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.