CAS: 78081-87-5; Fmoc-Lys(Fmoc)-Oh

相似化合物

75932-02-4 10009-20-8 105047-45-8

上下游产品

L-lysine N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide L-Lysine hydr°Chloride (fluorenylmethoxy)carbonyl chlorideL-lysine (S)-2,6-Diamino-hexanoic acid {2-[2-(2,4-dichloro-phenoxy)-acetylamino]-ethyl}-amide α,Nε-bis-Fm°C-L-Lys)-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamineN-(Nα,Nε-bis-Fm°C-L-Lys)-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine

9-芴甲基-N-琥珀酰亚胺基碳酸酯 反应生成 N,N'-双芴甲氧羰基-L-赖氨酸
参考文献:Fujii,Nobutaka;Futaki,Shiroh;Funakoshi,Susumu;Akaji,Kenichi;Morimoto,+,Chem. And Pharm. Bull.,36,(1988) N 9,C. 3281-3291
标题:Fujii,Nobutaka;Futaki,Shiroh;Funakoshi,Susumu;Akaji,Kenichi;Morimoto,+,Chem. And Pharm. Bull.,36,(1988) N 9,C. 3281-3291

专利信息

专利号:US-2024336649-A1
优先权日:2021-06-21
标 题 :Synthesis of covalent protein dimers that can inhibit myc-driven transcription
发明人：LOAS ANDREI; PENTELUTE BRADLEY L; POMPLUN SEBASTIAN; JBARA MUHAMMAD; SCHISSEL CARLY KATHERINE; RODRIQUEZ JACOB JOSHUA LEE; BUCHWALD STEPHEN LEFFLER; BOIJA ANN; KLEIN ISAAC; HAWKEN SUSANA WILSON; LI CHARLES HAN
权利人:MASSACHUSETTS INST TECHNOLOGY; WHITEHEAD INSTITUTE OF BIOMEDICAL RES
摘要:The disclosure relates to covalent protein dimers of MYC, MAX, and Omomyc; pharmaceutical compositions comprising the covalent protein dimers; methods of making the covalent protein dimers; and methods of treating disorders associated with MYC dysregulation (e.g., cancer) with the covalent protein dimers.

专利号:US-6175020-B1
优先权日:1999-04-09
标题 :Spirodiamino acid scaffold for combinatorial synthesis
发明人：DOLLE III ROLAND ELLWOOD; BARDEN MICHAEL C
权利人:PHARMACOPEIA INC
摘要:Azaspirononanes of formula I and their synthesis n are disclosed. The compounds are useful as templates for constructing synthetic receptors and as intermediates in the synthesis of enzyme inhibitors. They are prepared by an intramolecular ylide cycloaddition of a 6-hydrazone of 2,10-undecadienoic acid ester.

专利号:US-8178474-B1
优先权日:1999-04-21
标题 :Functionalised solid support for alpha-oxoaldehyde synthesis
发明人：MELNYK OLEG; FRUCHART JEAN-SEBASTIEN; BOUREL LINE; GRAS-MASSE HELENE
权利人:MELNYK OLEG; FRUCHART JEAN-SEBASTIEN; BOUREL LINE; GRAS-MASSE HELENE; PASTEUR INSTITUT; CENTRE NAT RECH SCIENT
摘要:The invention relates to a functionalised solid support for the synthesis of compounds comprising at least one α-oxoaldehyde function, to a process for preparing it and to its applications, in particular for the preparation of a library of organic compounds, of a diagnostic reagent, of a microtitration plate and of a biochip, such as a DNA chip. The present invention also relates to a process for the synthesis of organic compounds comprising at least one α-oxoaldehyde function and to the α-oxoaldehyde peptides obtained using this process.

专利号:US-8450469-B2
优先权日:2008-01-21
标 题:Synthesis of peptide nucleic acids conjugated with amino acids and their application
发明人：LEE HYUNIL; MIN JUNG HYUN
权利人:LEE HYUNIL; MIN JUNG HYUN; PANAGENE INC
摘要:This invention relates to a peptide nucleic acid (PNA) oligomer which is conjugated with one or more linear-type amino acid containing a plurality of alkyleneglycols and to a synthesis method thereof. In addition, this invention related to a linear amino acid spacer in a device for detection for detecting a target gene using the PNA oligomers which is fixed on a surface of a functionalized solid support. The linear amino acid spacer contains a plurality of alkyleneglycols and maintains enough space between the solid support and PNA oligomer in the device in order to prevent the interference of the interaction between the PNA oligomer and a target gene. Furthermore, this invention relates to a PNA array, a PNA chip and a gene diagnosis kit whereof sensitivity and specificity are improved by being manufactured with the PNA conjugated with the amino acid spacer.

专利号:US-6191277-B1
优先权日:1998-04-29
标 题:Hydroxypropylamide peptidomimetics as inhibitors of aspartyl proteases
发明人：DOLLE III ROLAND ELLWOOD; CAVALLARO CULLEN LEE; HERPIN TIMOTHEE FELIX
权利人:PHARMACOPEIA INC
摘要:Compounds of Formula Iare disclosed as inhibitors having activity against the aspartyl proteases, plasmepsin and cathsepsin D. The compounds are useful for treatment of diseases such as malaria and Alzheimer's disease. In preferred compounds of Formula I, Y is a heterocycle, amide, sulfonamide or carbamate and Z is an acyl or a functionalized acyl. Intermediates in the solid phase synthesis of compounds of Formula I, in which compounds are attached to a solid phase support, are also disclosed.

专利号:US-2025231184-A1
优先权日:2022-10-12
标题:Nitrilotriacetic acid linkers, solid phase synthesis of nitrilotriacetic acid linkers and applications thereof
发明人：JAMALI HOJJAT S
权利人:NICOYA LIFESCIENCES INC
摘要:Described are devices, compounds and methods for detecting an analyte in a sample. More particularly this disclosure provides SPR and LSPR sensors modified by NTA linkers for binding a ligand and/or analyte. The NTA linkers of the disclosure typically include a head (or “anchoring siteâ€?) for coupling to a surface of the SPR or LSPR sensor, a spacer, and one or more attachment sites on a distal end or ends of the spacer which couple to a ligand. The head may include a thiol for coupling the linker to a surface of the SPR or LSPR sensor. The spacer may be a carbon chain. PAG or PEG chain, or matrix material. The one or more attachment sites may be a nitrilotriacetic acid (NTA) moiety capable of chelating a transition metal ion and binding the ligand.