专利号:US-11891375-B2 优先权日:2021-07-26 标 题 :Method for the synthesis of 2,4-dimethylpyrimidin-5-ol, intermediates, and method for the synthesis of Lemborexant using the intermediates 发明人:AKHATOU ABDESLAM; DOBARRO RODRÃ?GUEZ ALICIA 权利人:MOEHS IBERICA SL 摘要:A method is for the synthesis of 2,4-dimethylpyrimidin-5-ol, which can be used as an intermediate compound in the synthesis of Lemborexant. The method includes reacting a nitrophenyl compound with N,N-dimethylformamide diethyl acetal.
专利号:US-5859288-A 优先权日:1995-03-24 标 题:Reagent and process for the synthesis of oxysulphide-containing fluorine-containing organic derivatives 发明人:FORAT GERARD; MAS JEAN-MANUEL; SAINT-JALMES LAURENT 权利人:RHONE POULENC CHIMIE 摘要:The invention relates to a reagent which is useful for the synthesis of oxysulphide-containing fluorine-containing organic derivatives by reacting with an oxide of sulphur, especially sulphur dioxide, characterized in that it comprises: a) a fluorocarboxylic acid of formula Ew-CF2-COOH where Ew is an electron-withdrawing group or atom which is at least partially salified by an organic or inorganic cation, and b) an aprotic polar solvent; and in that the content of releasable protons carried by its various components, including their impurities, is at most equal to half the initial molar concentration of the said fluorocarboxylic acid. This reagent can be used by heating in order to form fluorine-containing sulphinic or sulphonic acids.
专利号:US-9073758-B2 优先权日:2011-04-21 标 题 :Synthesis of metal borides 发明人:KOC RASIT; MAWDSLEY JENNIFER R; CARTER JOHN DAVID 权利人:KOC RASIT; MAWDSLEY JENNIFER R; CARTER JOHN DAVID; UCHICAGO ARGONNE LLC 摘要:Methods for the synthesis of metal borides. Metal boride compounds synthesized by those methods are also disclosed.
专利号:US-8287715-B2 优先权日:2009-05-19 标题:Synthesis of boron using molten salt electrolysis 发明人:TAYLOR PATRICK R; GOMEZ JUDITH C 权利人:TAYLOR PATRICK R; GOMEZ JUDITH C; COLORADO SCHOOL OF MINES 摘要:The invention relates generally to elemental boron, particularly to elemental boron having a high purity level and to a method of recovering elemental boron by the electrolysis of a molten boron-containing electrolyte.
专利号:US-2005136439-A1 优先权日:2003-09-12 标题:Novel methods of inorganic compound discovery and synthesis 发明人:EATON BRUCE E; FELDHEIM DANIEL L; DOLSKA MAGDA; GUGLIOTTI LINA A 权利人:UNIV NORTH CAROLINA STATE 摘要:The present invention provides methods for the synthesis and/or discovery of inorganic compounds, including organometallic compounds. Also provided are functional nucleic acids for synthesis of inorganic compounds and methods of identifying the same. As another aspect, the invention provides compounds made according to the inventive methods, including palladium plates and cobalt-iron oxides spheres, cubes, fibers and nanotubes.
专利号:US-2023091493-A1 优先权日:2020-02-14 标 题:Dna synthesis yield improvements 发明人:ROTHWELL PAUL; KYSH DANIEL; PORTER NEIL 权利人:TOUCHLIGHT IP LTD 摘要:The present invention relates to an improved process for synthesis of deoxyribonucleic acid (DNA), in particular cell-free enzymatic synthesis of DNA, preferably on a large or industrial scale, with an improved yield and/or with an improved efficiency. The invention requires the use of nucleotide complexes wherein the nucleotide is associated with a mixture of divalent and monovalent cations. Preferably, the divalent cation may be magnesium or manganese.
参考文献:10.1016/j.apradiso.2017.01.035 摘要:Crawford JR, Kunz P, Yang H, Schaffer P, Ruth TJ. 211 Rn/ 211 At and 209 At production with intense mass separated Fr ion beams for preclinical 211 At-based α-therapy research. Applied Radiation and Isotopes. 2017 Apr;122():222–8. doi: 10.1016/j.apradiso.2017.01.035. 摘要:Merck Index - O'Neil MJ, Heckelman PE, Dobbelaar PH, Roman KJ (eds). The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 15th Ed. Cambridge, UK: The Royal Society of Chemistry, 2013. 参考文献:10.1016/s0021-9673(01)97370-4 摘要:Nelson F, Michelson DC, Phillips HO, Kraus KA. Ion exchange procedures. VII. Separation of alkali metal ions. J Chromatogr. 1965 Oct;20(1):107–21. doi: 10.1016/s0021-9673(01)97370-4.