CAS: 54004-38-5; 7-Methylisoquinoline

上下游产品

CAS号24188-80-5 1-氯-7-甲基异喹啉 | CAS号7480-80-0 5-methyl-1h-indene | CAS号10034-85-2 氢碘酸 | CAS号87087-20-5 异喹啉-7-甲醛

📜Formic Acid-(β-Hydroxy-4-Methyl-Phenethylamide)置于phosphorus Pentoxide,Xylene,三氯氧磷体系中,化学反应生成 7-甲基异喹啉
参考文献:Rodionow Et Al.,Zhurnal Obshchei Khimii,1957,Vol. 27,P. 734,739; Engl. Ausg. S. 809,813
标题:Rodionow Et Al.,Zhurnal Obshchei Khimii,1957,Vol. 27,P. 734,739; Engl. Ausg. S. 809,813

专利信息

专利号:US-8642766-B2
优先权日:2008-05-05
标题 :Synthesis of (+) cortistatin A and related compounds
发明人：SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
权利人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
摘要:An in vitro synthesis of (+) cortistatin A from readily available precursors is disclosed, as are the syntheses of related 17-aryl substituted compounds, the 17-aryl substituted compounds themselves and novel compounds useful in their preparation.

专利号:US-7935827-B2
优先权日:2003-12-31
标题 :Optically active, heteroaromatic β-hydroxy esters and processes for their preparation from β-keto esters and processes for the preparation of these β-keto esters
发明人：PLATZEK JOHANNES; ZORN LUDWIG; BUCHMANN BERND; SKUBALLA WERNER; PETROV ORLIN
权利人:BAYER SCHERING PHARMA AG
摘要:The present invention relates to new optically active heteroaromatic β-hydroxy esters useful in the synthesis of epothilone derivatives, to certain compounds used to produce these intermediates, as well as to processes for their production.

专利号:US-6140505-A
优先权日:1995-03-10
标 题:Synthesis of benzo fused heterocyclic sulfonyl chlorides

专利号:US-2011060140-A1
优先权日:2008-05-05
标题:Synthesis of (+) cortistatin a and related compounds

专利号:US-2008096883-A1
优先权日:2004-08-11
标题 :Trifluoromethyl substituted benzamides as kinase inhibitors
发明人：CARAVATTI GIORGIO; FURET PASCAL; IMBACH PATRICIA; MARTINY-BARON GEORG; PEREZ LAWRENCE BLAS; SHENG TAO
权利人:CARAVATTI GIORGIO; FURET PASCAL; IMBACH PATRICIA; MARTINY-BARON GEORG; PEREZ LAWRENCE BLAS; SHENG TAO
摘要:The invention relates to trifluoromethyl substituted benzamide compounds of the formula (I), pharmaceuticals comprising these compounds, their use as or for the manufacture of pharmaceuticals, particularly as inhibitors of protein kinases and/or the treatment of a condition, disorder or disease state mediated by a protein kinase activity and/or a proliferative disease, methods of treatment comprising administering the compounds, especially of therapeutic and prophylactic treatment, methods for the manufacture of the compounds and novel intermediates and partial steps for their synthesis.

专利号:US-8754237-B2
优先权日:2006-02-14
标题:Bifunctional histone deacetylase inhibitors
发明人：BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L
权利人:BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.