CAS: 519-34-6; (3,4-Dihydroxyphenyl)(2,4,6-Trihydroxyphenyl)Methanone

该化合物是一种自然产生的氟氯素化合物,主要产自马克卢拉松木树的树皮,通称为Osage橙,其特点是黄色,以其抗氧化特性著称,有助于其潜在的健康惠益.Maclurin展示了一种酚状结构,这是氟氯素的典型,允许其参与各种生物化学互动.该化合物引起了人们对研究其潜在的反炎,抗微生物和抗癌症活动的兴趣.此外,马克鲁林在有机溶剂中溶解,但水溶解性有限,可影响其生物利用率和各种配方的应用.一般认为,其安全性特征是有利的,但需要进一步研究,以充分了解其药用植物学和治疗潜力.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号58262-60-5 2,3',4,4',6-pen... | CAS号108-73-6 间苯三酚 | CAS号17345-61-8 3,4-二羟基苯甲腈 | CAS号10135-18-9 diethyl 2,4,6-t... | CAS号3542-72-1 芒果苷元 | CAS号59092-97-6 isoathyriol | CAS号480-20-6 二氢莰非醇； 香橙素 | CAS号124-38-9 二氧化碳 | CAS号120-80-9 邻苯二酚 | CAS号108-73-6 间苯三酚 | CAS号99-50-3 原儿茶酸 | CAS号3542-72-1 芒果苷元

合成工艺路线路线简述

  • 合成目标产物 2,3',4,4',6-Pentahydroxybenzophenone 主要起始原料 Norathyriol
  • (文献来源)合成步骤主要原料 Norathyriol
📜2,3',4,4',6-Pentamethoxybenzophenone置于三氯化铝,甲苯体系中,化学反应生成 2,3',4,4',6-五羟基二苯甲酮
参考文献:Chemical Constitution And The Tanning Effect. Iii. Polyhydroxybenzophenones
标题:Chemical Constitution And The Tanning Effect. Iii. Polyhydroxybenzophenones
摘要:
DOI:10.1021/ja01179A024

海关参考信息

专利信息


专利号:US-11312696-B2
优先权日:2017-11-21
标 题:Synthesis of morin and morin derivatives
发明人：LINDEL THOMAS; MENDE STEFFEN
权利人:ORSATEC GMBH
摘要:The invention relates to a method for directly producing morin derivatives and high-purity morin of formula (I). The invention also relates to morin derivatives and high-purity morin that can be obtained using the claimed method.

专利号:US-2020308131-A1
优先权日:2017-11-21
标 题 :Synthesis of morin and morin derivatives

专利号:EP-0706089-A3
优先权日:1994-10-05
标 题 :Process for the synthesis of a quinonediazide ester and positive working photoresist containing it

专利号:EP-3713925-A1
优先权日:2017-11-21
标题 :Synthesis of morin and morin derivatives

专利号:WO-2019101353-A1
优先权日:2017-11-21
标 题:Synthesis of morin and morin derivatives

专利号:EP-3486240-A1
优先权日:2017-11-21
标 题:Synthesis of morin and morin derivatives

其他信息查阅

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品牌试剂参考报价(招募中)

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⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Li X, Gao Y, Li F, Liang A, Xu Z, Bai Y, Mai W, Han L, Chen D. Maclurin protects against hydroxyl radical-induced damages to mesenchymal stem cells: antioxidant evaluation and mechanistic insight. Chem Biol Interact. 2014 Aug 5;219:221-8. doi: 10.1016/j.cbi.2014.06.014. Epub 2014 Jun 25. doi: 10.1007/s11010-015-2331-4. Epub 2015 Jan 29.
4: Kaya D, Jäger AK, Yalçin FN, Ersöz T. MAO-A inhibition profiles of some benzophenone glucosides from Gentiana verna subsp. pontica. Nat Prod Commun. 2014 Apr;9(4):505-6. doi: 10.1016/j.fitote.2013.07.020. Epub 2013 Aug 3. doi: 10.1080/14786419.2015.1004175. Epub 2015 Jan 27. doi: 10.1007/s00216-015-8648-8. Epub 2015 Apr 21. doi: 10.1186/s12906-016-1340-5.
9: Beelders T, de Beer D, Stander MA, Joubert E. Comprehensive phenolic profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS reveals novel xanthone and benzophenone constituents. Molecules. 2014 Aug 7;19(8):11760-90. doi: 10.3390/molecules190811760. doi: 10.1021/ol302283p. Epub 2012 Sep 17. doi: 10.1016/j.jgr.2017.11.003. Epub 2017 Nov 21.

合成参考文献


摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1016/s0304-3835(98)00173-6
摘要:Ito C, Itoigawa M, Furukawa H, Rao KS, Enjo F, Bu P, Takayasu J, Tokuda H, Nishino H. Xanthones as inhibitors of Epstein-Barr virus activation. Cancer Lett. 1998 Oct 23;132(1-2):113–7. doi: 10.1016/s0304-3835(98)00173-6.
摘要:Tátrai E, Ungváry G, Adamis Z. On the structural differences in the membranes between ciliated bronchial and non-ciliated lymphoepithelium in rats. Eur J Histochem. 1994;38(1):59–64.
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