CAS: 37675-18-6; (S)-Ethyl Piperidine-3-Carboxylate

相似化合物

5006-62-2 130250-54-3 194726-40-4

上下游产品

3-哌啶甲酸乙酯 Ethyl Nipecotate 5006-62-2
(S)-3-哌啶甲酸 (S)-Nipecotic Acid 59045-82-8

3-哌啶甲酸乙酯 反应生成(S)-3-哌啶甲酸乙酯
参考文献: N-Heterocyclyl-Substituted Amino-Thiazole Derivatives As Protein Kinase Inhibitors[fr] Derives D'Amino-Thiazole Substitues Par N-Heterocyclyle En Tant Qu'Inhibiteurs De La Proteine Kinase
标题: N-Heterocyclyl-Substituted Amino-Thiazole Derivatives As Protein Kinase Inhibitors[fr] Derives D'Amino-Thiazole Substitues Par N-Heterocyclyle En Tant Qu'Inhibiteurs De La Proteine Kinase
摘要:Aminothiazole化合物在2-氨基位置带有n-含氮环烷基,其化学式表示为(i),或者该化合物的药学上可接受的前药,或者该化合物的药学上可接受的盐,可以调节和/或抑制细胞增殖和蛋白激酶活性.

专利信息

专利号:US-7692019-B2
优先权日:2000-12-04
标 题:Methods for the stereoselective synthesis of substituted piperidines
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HEFFERNAN MICHELE L R; HOEMANN MICHAEL Z; KESSLER DONALD W; SHAO LIMING; WU XINHE; XIE ROGER L
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.

专利号:US-7816375-B2
优先权日:2000-09-11
标 题 :Ligands for monoamine receptors and transporters, and methods of use thereof
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HOLLAND JOANNE M; PERSONS PAUL E; RADEKE HEIKE; WANG FENGJIANG; SHAO LIMING
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.

专利号:US-2002177721-A1
优先权日:2000-12-04
标题 :Methods for the stereoselective synthesis of substituted piperidines

专利号:US-2006211864-A1
优先权日:2000-12-04
标题:Methods for the stereoselective synthesis of substituted piperidines

专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.

专利号:US-2004235893-A1
优先权日:2000-12-04
标题 :Methods for the stereoselective synthesis of substituted piperidines