专利号:US-9267213-B1 优先权日:2005-03-25 标题:Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array 发明人:MAURER KARL; COOPER JOHN J 权利人:CUSTOMARRAY INC 摘要:There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.
专利号:US-5414094-A 优先权日:1990-01-26 标 题 :High purity and high yield synthesis of dianhydrides 发明人:CSAPILLA JOSEPH 权利人:CYTEC TECH CORP 摘要:A process for making a dianhydride product, said process comprising reacting two moles of maleic anhydride and one mole of a vinyl benzene compound in a reaction mixture comprising about 1.5 to 2.0 moles of the vinyl benzene compound per mole of maleic anhydride at reaction temperature in the range from 105° to 125° C. for time to complete the reaction, adding a polar organic liquid to the reaction product mixture and refluxing the mixture, cooling the mixture following reflux and adding a hydrocarbon liquid to precipitate the product, separating the solid dianhydride product by filtration, washing the solids on the filter and drying the solids to make the finished dianhydride product.
专利号:US-2022323924-A1 优先权日:2021-03-24 标题:Electrochemical polynucleotide synthesis 发明人:LACKEY JEREMY; HABIBIAN MARYAM; LIN YANYOU 权利人:TWIST BIOSCIENCE CORP 摘要:Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) Further provided are compositions for low voltage deprotection of polynucleotides.
专利号:US-4609739-A 优先权日:1984-11-06 标 题:Synthetic routes to benzofurans and benzothiophenes and intermediates therefor 发明人:GAMMILL RONALD B 权利人:UPJOHN CO 摘要:The present invention provides novel compositions of matter and processes for their preparation. More particularly, the present invention consists of novel chemical intermediates and associated processes for the preparation of khellin and other furochromone analogues, which have demonstrated antiatherosclerotic activity. These novel intermediates and processes can also be used for the preparation of benzofurans and benzothiophenes which inhibit the synthesis of leukotriene and/or lipoxygenase.
专利号:MX-2007011815-A 优先权日:2005-03-25 标题 :ELECTROCHEMICAL UNLOCK SOLUTION FOR ELECTROCHEMICAL SYNTHESIS OF OLIGOMEROS IN AN ARRANGEMENT OF ELECTRODES.
专利号:RU-2007139631-A 优先权日:2005-03-25 标题 :SOLUTION FOR ELECTROCHEMICAL DEPARTMENT IN ELECTROCHEMICAL SYNTHESIS OF OLIGOMERS ON THE ELECTRODE MATRIX
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合成参考文献
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