CAS: 22317-01-7; 1,3-Dimethylpiperazine

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CAS号109055-55-2 1-benzyl-2,4-di... | CAS号29906-54-5 1-苄基-2-甲基哌嗪 | CAS号23936-11-0 3-甲基-2-羰基哌嗪 | CAS号29906-47-6 1-benzyl-2-meth... | CAS号114649-85-3 1-Piperazinecar... | CAS号69628-30-4 11-[2-(2,4-dime...

📜3-甲基-2-氧代-哌嗪置于palladium On Activated Charcoal Lithium Aluminium Tetrahydride,甲酸,氢气体系中,用 四氢呋喃,甲醇,溶剂黄146 用作溶剂,化学反应 118.0H,反应生成1,3-二甲基-哌嗪
参考文献:Charles,Elisabeth S.; Sharma,Satyavan,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1987,Vol. 26,# 1-12,P. 752-756
标题:Charles,Elisabeth S.; Sharma,Satyavan,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1987,Vol. 26,# 1-12,P. 752-756

专利信息

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:US-4381301-A
优先权日:1980-05-07
标题 :Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
发明人：RAINER GEORG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:Substituted thienobenzodiazepinones of the general formula I (I) [wherein R1 denotes a hydrogen atom (-H) or an alkyl radical with 1 to 4 carbon atoms; R2 represents a halogen atom (halo) or has one of the meanings of R1; R3 denotes a halogen atom (halo) or the group -N(R4)R5; R4 denotes an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms; R5 has one of the meanings of R4 or represents the group -(CH2)m-N(R6)R7; or R4 and R5, together with the nitrogen atom to which both are bonded, denote a morpholino group, a pyrrolidino group, a piperidino group, a hexahydroazepin-1-yl group, a piperazin-1-yl group (which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group), a 2,4-dimethylpiperazin-1-yl group, or a hexahydro-1H-1,4-diazepin-1-yl group (which is substituted in the 4-position by a methyl or ethyl group); R6 denotes an alkyl group with 1 to 4 carbon atoms; R7 denotes an alkyl group with 1 to 4 carbon atoms; A denotes a straight-chain or branched alkylene group with 1 to 5 carbon atoms; and m denotes 2 or 3] and their acid-addition salts are new compounds. They either have a protective action on the stomach and intestine and are suitable for treating illnesses based on disorders of the stomach or intestine, or they are intermediates for preparing products having protective action. Processes for the preparation of the new pharmacologically-active compounds and of the intermediate products are presented.

专利号:US-6777420-B2
优先权日:2001-06-15
标题 :Heterocyclic antibacterial compounds
发明人：ZHI CHENGXIN; WRIGHT GEORGE E
权利人:MICROBIOTIX INC
摘要:The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.

专利号:US-4317823-A
优先权日:1979-08-03
标题 :Pyrazolobenzodiazepinones, their intermediates, their compositions and their use
发明人：RAINER GEORG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:1-(Lower)alkyl-4-(substituted)aminoalkylcarbonyl-1,4,9,10-tetrahydropy razolo[4,3-b][1,5]benzodiazepin-10-ones are useful, e.g., to protect warm blooded animals against the formation of gastric ulcers. They are active ingredients in otherwise conventional medicament compositions administered enterally or parenterally in standard dosage forms. Their synthesis, their novel intermediates and their acid-addition salts are described.

专利号:US-6271235-B1
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.