CAS: 19432-68-9; Methyl 2-Thienylacetate

上下游产品

diazomethane 2-Thiophenecarbonyl chloride methanol Thiophene-2-acetic acid5-(2-cloro-4-nitrobenzoil)tiofen-2-acetato di metile 2-thiophenethanol (5-bromo-thiophen-2-yl)-acetic acid methyl ester [5-(3-amino-phenyl)-thiophen-2-yl]-acetic acid methyl ester

2-噻吩乙酸置于氯化亚砜体系中,化学反应 3.0H,反应生成噻吩-2-乙酸甲酯
参考文献:Synthesis Of Selective Srpk-1 Inhibitors: Novel Tricyclic Quinoxaline Derivatives
标题:Synthesis Of Selective Srpk-1 Inhibitors: Novel Tricyclic Quinoxaline Derivatives
摘要:Sr Protein-Specific Kinase-1 (Srpk-1) Has Been Identified As A Validated Target For Hepatitis B Virus (Hbv). A Series Of Novel Tricyclic Quinoxaline Derivatives Was Designed And Synthesised As Potential Kinase Inhibitory Antiviral Agents And Was Found To Be Active And Selective For Srpk-1 Kinase. Most Of These Novel Compounds Have Drug-Like Properties According To Experimentally Determined Log P And Log S Values. (C) 2005 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2005.04.064

专利信息

专利号:US-4340672-A
优先权日:1979-09-19
标 题:Enzymatic synthesis of β-lactam antibacterials
发明人：KONDO EIJI; MITSUGI TAKASHI; FUJIWARA TAMIO; MUNEYUKI RYONOSUKE
权利人:SHIONOGI & CO
摘要:Penicillins and cephalosporins can be synthesized by the action of an acylase on a penicillin or cephalosporin nucleus amine as substrate and an ester (I) of the following formula as the acyl source: (I) (wherein RCO is an acyl group in penicillin or cephalosporin side chains; X is a hydrogen atom, lower alkyl group or hydroxy-lower alkyl group; Y is a hydrogen atom or a lower alkyl group; and n is a positive integer). The novel acyl source (I) is also disclosed.

专利号:GB-2058776-A
优先权日:1979-09-19
标题:Esters and their use in the synthesis of -lactam antibacterial compounds

专利号:US-9334304-B2
优先权日:2009-04-02
标 题:Self-assembling peptides bearing organic electronic functionality and applications employing the same
发明人：TOVAR JOHN DAYTON; DIEGELMANN STEPHEN ROBERT; WALL BRIAN D; VADEHRA GEETA SOPHIE
权利人:TOVAR JOHN DAYTON; DIEGELMANN STEPHEN ROBERT; WALL BRIAN D; VADEHRA GEETA SOPHIE; UNIV JOHNS HOPKINS
摘要:The aqueous self-assembly of oligopeptide-flanked Ï€-conjugated molecules into discrete one-dimensional nanostructures is described. Unique to these molecules is the fact that the Ï€-conjugated unit has been directly embedded within the peptide backbone by way of a synthetic amino acid with Ï€-functionality that is compatible with standard Fmoc-based peptide synthesis or by way of a diacid or other bis(electrophile) that can covalently cross-link peptide chains presented on a synthesis support. The peptide-based molecular designs enforce intimate Ï€-Ï€ communication within the aggregates after charge-screening and self-assembly, making these nanostructures attractive for optical or electronic applications in biological environments. In other embodiments, a convenient method to incorporate Ï€-electron units into peptides that assemble into amyloid-like supramolecular polymers is disclosed. Self-assembly manipulates these “electronic peptidesâ€? into delocalized sub-10 nm one dimensional (1-D) nanostructures under compltely aqueous conditions.

专利号:FR-2465708-A1
优先权日:1979-09-19
标 题:PROCESS FOR SYNTHESIZING PENICILLINS AND CEPHALOSPORINS BY ACTION OF AMIDOACYLASE, AND ESTERS AS SOURCES OF ACYLATED GROUPS FOR THIS SYNTHESIS