CAS: 121-29-9; Pyrethrin Ii

上下游产品

methyl (1R,3R)-3-formyl-2,2-dimethylcyclopropanecarboxylate (S)-(+)-pyrethrolone ethyl trans-(+/-)-chrysanthemate trans-chrysanthemic acid8',9'-epoxypyrethrin II 10',11'-epoxypyrethrin II 8',9'-dihydroxypyrethrin II jasmolin II

📜菊酸乙酯置于四氢吡咯,N-甲基咪唑,Sodium Chlorite,Sodium Dihydrogenphosphate,2-甲基-2-丁烯,(S)-(-)-1-(1-萘基)乙胺,Sodium Hydride,Potassium Carbonate,臭氧,N,N-二异丙基乙胺,对甲苯磺酰氯,Potassium Hydroxide体系中,用 甲醇,5,5-Dimethyl-1,3-Cyclohexadiene,乙醇,正己烷,水,甲苯,乙腈,Mineral Oil,叔丁醇 用作溶剂,化学反应 49.5H,反应生成除虫菊素
参考文献:全部六种手性天然菊酯的总合成:物理性质,杀虫活性的准确测定以及合成方法的评估.
标题:全部六种手性天然菊酯的总合成:物理性质,杀虫活性的准确测定以及合成方法的评估.
摘要:菊花(解热丝)花中所含的全部六个杀虫性天然除虫菊酯(三个除虫菊酯i和三个除虫菊酯ii化合物)的手性总合成.合成了三种常见的醇成分[(S)-香气酮,(S)-茉莉香酮和(S)-吡咯烷酮]:(i)使用可用的(S)-4-羟基-3-甲基的直接sonogashira型交叉偶联剂(S)-苯环戊酮(总产率52%,Ee 98%)和(S)-吡咯烷酮(总产率54%) 98%ee)和(II)(S)-茉莉醇酮的传统脱羧-醛醇缩合和脂肪酶催化的光学拆分(总收率16%,Ee为96%).制备了两个反酸链段[(1R,3R)-菊酸(a)和(1R,3R)-第二菊酸前体(b)]:(i)c(1)-(+/-)-菊苣酸酯的差向异构化,并使用(S)-萘乙胺进行光学拆分,得到a(96%ee),以及(II)a简化为b的衍生化(96%ee).使用易得的酯化试剂(tscl / N-甲基咪唑)成功合成了全部六个除虫菊酯(cinerin I / Ii,茉莉素i
Doi:10.1021/acs.Joc.9B02767

专利信息

专利号:US-6750049-B1
优先权日:1999-03-23
标题 :Synthesis of 1,2,3,4-tetrahydroxybenzenes and 1,2,3-trihydroxybenzenes using myo-inositol-1-phosphate synthase and myo-inositol 2-dehydrogenase
发明人：FROST JOHN W; HANSEN CHAD A
权利人:UNIV MICHIGAN STATE
摘要:A bioengineered synthesis scheme for the production of 1,2,3,4-tetrahydroxybenzene from a carbon source is provided. Methods of producing 1,2,3,4-tetrahydroxybenzene from a carbon source based on the synthesis scheme are also provided. Methods are also provided for converting 1,2,3,4-tetrahydroxybenzene to 1,2,3-trihydroxybenzene by catalytic hydrogenation.

专利号:US-5443978-A
优先权日:1993-03-11
标 题 :Chrysanthemyl diphosphate synthase, corresponding genes and use in pyrethrin synthesis
发明人：ELLENBERGER SUZANNE R; PEISER GALEN D; BELL RUSSELL N; HUSSEY JR CHARLES E; SHATTUCK-EIDENS DONNA M; SWEDLUND BRADLEY D
权利人:AGRIDYNE TECH INC
摘要:This invention provides a purified chrysanthemyl diphosphate synthase (CDS), a method for the purification of CDS from Chrysanthemum cinerariaefolium, and an amino acid sequence of the isolated CDS. Also provided is a cDNA encoding the CDS, a nucleotide sequence of the CDS gene, and a derived amino acid sequence of the encoded CDS protein. The CDS gene is useful in the enzymatic production of the natural stereospecific configuration of chrysanthemyl derivatives which are useful for the synthesis of pyrethrins, pyrethroids, derivatives thereof, as well as other classes of metabolites.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人：EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-3978093-A
优先权日:1971-06-29
标 题:Synthesis of hydroxycyclopenten-1-ones
发明人：BUCHI GEORGE
权利人:HOFFMANN LA ROCHE
摘要:This invention relates to a process for the preparation of 2-alkenyl-4-hydroxy-3-methyl-2-cyclopenten-1-ones from the reaction product of 2,4-pentane dione and a 2-propen-or 2-propyn-1-ol derivative including intermediates therein.

专利号:US-4071542-A
优先权日:1976-04-28
标 题 :Synthesis of hydroxycyclopenten-1-ones
发明人：BUCHI GEORGE
权利人:HOFFMANN LA ROCHE
摘要:This invention relates to a process for the preparation of 2-alkenyl-4-hydroxy-3-methyl-2-cyclopenten-1-ones from the reaction product of 2,4-pentane dione and a 2-propen- or 2-propyn-1-ol derivative including intermediates therein.