CAS: 12071-83-9; Propineb

该化合物是其广谱性功效,使其能有效对抗低温,叶斑和枯叶等病原体;配方通常含有高浓度的活性成分,从而提高其预防和控制真菌感染的效力;一般用作花生喷雾,因其保护性行动而闻名,防止真菌发芽,防止植物组织繁殖和感染;此外,70型杀菌剂在使用建议的准则时对非目标生物体的毒性较低,因此得到承认;但是,与所有杀虫剂一样,必须遵循安全防范措施和条例,以尽量减少环境影响并确保安全处理.

结构式图片

欧盟法规

ECHA物质欧盟农药活性物质ECHA物质OtherC&L通报REACH预注册

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    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-2016073631-A1
    优先权日:2013-03-04
    标 题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-9233920-B2
    优先权日:2010-06-11
    标题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:WO-2023089578-A1
    优先权日:2021-11-22
    标题:A synthesis process of iron-bearing compositions and possible additional essential elements
    发明人:MORMILE SILVIA; GUSMEROLI MARILENA; ZANARDI GIAMPAOLO; BIANCHI DANIELE; COTROMINO MICHELE; SARGIOTTO CHIARA; LIGUORI RICCARDO
    权利人:GOWAN CROP PROT LIMITED
    摘要:A synthesis process of iron-bearing compositions and possible additional essential elements is described for treating nutritional deficiencies in plants, in particular for the prevention and treatment of physiological alterations or nutritional unbalances in plants due to the deficiency of iron and other essential elements, and the iron-bearing compositions and possibly further essential elements obtained with said process.

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

    专利号:US-9968097-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
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    主要参考文献


    1: Rasgele PG, Muranli FD, Kekeçoğlu M. Assessment of the genotoxicity of propineb in mice bone marrow cells using micronucleus assay. Tsitol Genet. 2014 Jul-Aug;48(4):39-43. doi: 10.2478/10004-1254-65-2014-2408. doi: 10.1007/s10661-009-1234-9. Epub 2009 Nov 13. doi: 10.1128/AAC.05146-14. Epub 2015 Jan 26.
    5: Parihar NS, Sharma BN. Persistence of propineb (polymeric zinc 1,2-propylene bisdithiocarbamate) fungicide in onion and cropped soil. Bull Environ Contam Toxicol. 2011 May;86(5):545-7. doi: 10.1007/s00128-011-0256-5. Epub 2011 Mar 27. doi: 10.1016/j.toxlet.2008.08.016. Epub 2008 Sep 4. Epub 2007 Mar 21. doi: 10.1007/s10646-014-1303-x. Epub 2014 Aug 20. Epub 2002 May 29. Italian.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:Kanerva - Rustemeyer L, Elsner P, John SM, Maibach HI (eds). Kanerva's Occupational Dermatology, 2nd Ed. Berlin: Springer-Verlag, 2012., p. 1847
    摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382.
    参考文献:10.1007/s00204-002-0353-7
    摘要:Schmuck G, Ahr HJ, Mihail F, Stahl B, Kayser M. Effects of the dithiocarbamate fungicide propineb in primary neuronal cell cultures and skeletal muscle cells of the rat. Arch Toxicol. 2002 Jul;76(7):414–22. doi: 10.1007/s00204-002-0353-7.
    参考文献:10.1016/j.talanta.2009.10.026
    摘要:Flampouri K, Mavrikou S, Kintzios S, Miliadis G, Aplada-Sarlis P. Development and validation of a cellular biosensor detecting pesticide residues in tomatoes. Talanta. 2010 Mar 15;80(5):1799–804. doi: 10.1016/j.talanta.2009.10.026.
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