CAS: 78646-25-0; 4-(Dimethylamino)-1-Tritylpyridin-1-Ium Chloride

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上下游产品

CAS号1122-58-3 4-二甲氨基吡啶 | CAS号76-83-5 三苯基氯甲烷 | CAS号1420-06-0 杀螺吗啉 | CAS号20020-75-1 N-tritylprop-2-... | CAS号13515-76-9 N-(三苯基甲基)-DL-丝氨酸甲酯 | CAS号18514-46-0 N-(三苯甲基)甘氨酸乙酯 | CAS号5333-62-0 (diphenyl-pheny...

📜4-二甲氨基吡啶,三苯基氯甲烷 以 二氯甲烷 作为反应溶剂,以99%的收率获得产物4-(二甲氨基)-1-(三苯甲基)吡啶氯化物
参考文献:"单击"双三唑为中性c吗h⋅⋅⋅阴离子受体有机催化剂
标题:"单击"双三唑为中性c吗h⋅⋅⋅阴离子受体有机催化剂
摘要:球场上的新球员!"点击"双-三唑已被引入作为高效率的新型类中性的c  H⋅⋅⋅anion结合有机催化剂(参见方案).dft和NMR研究用于确认这种活化方式并确定最佳催化剂.
DOI:10.1002/chem.201203360

专利信息

专利号:WO-2007009944-A1
优先权日:2005-07-21
标 题 :Tritylation reactions based on metallic catalysis
发明人：MALTESE MAURIZIO
权利人:UNIV ROMA; MALTESE MAURIZIO
摘要:The invention relates to a method for preparing tritylated compounds in which protic functional groups are protected with the triphenylmethyl group, method based on the homogeneous catalysis exercised by salts or metal complexes in organic solvents. The invention relates in particular to a method for the selective tritylation of some groups, obtained both directly and by selective detritylation, with methods based on metallic catalysis. The application to amino acids, typical substrates not suitable to be subjected as such to homogeneous tritylations in organic solvents, indicates the ability of the method to extend also to hydrophilic substrates. The method allows to obtain with high yield pertrityl amino acids, N-tritylamino acids or amino acids tritylated only in lateral chain, compounds which heretofore were either difficult to obtain in aqueous solvents or obtainable through indirect methods. All, in any case, are important intermediates in peptide synthesis.