CAS: 62890-98-6; Magnesium,1,4-Dimethoxybenzene-6-Ide,Bromide

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CAS号25245-34-5 2,5-二甲氧基溴苯 | CAS号150-78-7 对苯二甲醚 | CAS号40180-96-9 1-(2,5-dimethox...

📜1-溴-2,5-二甲氧基苯置于magnesium体系中,用 四氢呋喃 作为反应溶剂,化学反应 1.5H,反应生成 2,5-二甲氧基苯基溴化镁
参考文献:铜催化β,γ-不饱和羧酸的二氟甲基化:有效的烯丙基二氟甲基化
标题:铜催化β,γ-不饱和羧酸的二氟甲基化:有效的烯丙基二氟甲基化
摘要:不是一个而是两个!已经开发了具有烯丙基cf 2 H基团的化合物的区域特异性构建的新策略.的β,γ不饱和羧酸的脱羧(苯基磺酰基)二氟甲基是由一种路易斯酸(催化的cucl 2 ⋅2ħ 2 O),将所得产物容易发生脱磺酰.
DOI:10.1002/anie.201206556

专利信息

专利号:US-5998620-A
优先权日:1997-03-25
标 题 :Synthesis of intermediates useful in preparing tricyclic compounds
发明人：CHEN XING; POIRIER MARC; WONG YEE-SHING; WU GUANG-ZHONG
权利人:SCHERING CORP
摘要:The invention relates to a process for preparing a compound of the formula ##STR1## comprising reacting a bromo-substituted pyridine with an amine of the formula NHR 5 R 6 , reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R 1 , R 2 , R 3 and R 4 are as defined in the specification; also claimed are a compound of the formula ##STR2## and a process for preparing it from the corresponding halo-substituted benzoic acid.

专利号:EP-0977739-B1
优先权日:1997-03-25
标题 :Synthesis of intermediates useful in preparing tricyclic compounds
发明人：CHEN XING; POIRIER MARC; WONG YEE-SHING; WU GUANG-ZHONG
权利人:SCHERING CORP
摘要:The invention relates to a process for preparing a compound of formula (I), comprising reacting a bromo-substituted pyridine with an amine of the formula NHR5R6, reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R?1, R2, R3 and R4¿ are as defined in the specification; also claimed are a compound of formula (a), and a process for preparing it from the corresponding halo-substituted benzoic acid.

专利号:WO-9842676-A1
优先权日:1997-03-25
标 题:Synthesis of intermediates useful in preparing tricyclic compounds

专利号:EP-0977739-A1
优先权日:1997-03-25
标题 :Synthesis of intermediates useful in preparing tricyclic compounds