CAS: 4923-84-6; Tert-Butylphosphonic Acid

该化合物是一种有机磷化合物,其特征是其磷酸功能组,附于三丁基甲基混合物,这种结构具有阻碍和稳定性,使其作为催化液的悬浮剂和有机合成的前体有用,其酸性能和发泡能力使化学协调应用得以应用,特别是在稳定金属复合体方面. 异丁基混合物可增强有机溶剂的溶性,促进其在同质反应系统中的使用.该化合物还用于地表改变的材料科学以及作为制药和农用化学合成的中间体.在各种条件下,其定义明确的再活性和强性使其在研究和工业过程中成为多用途试剂.

结构式图片

欧盟法规

[ECHA物质C&L通报

上下游产品

P,1,2-Tri-tert-butylhydrazidophosphonsaeure-tert-butylester P,1,2-Tri-tert-butylhydrazidophosphonsaeure-methylesterIsobutane isobutene 5O3(tert-butylphosphonate)2(PhCOO)5(1,10-phenanthroline)2]*H2O*(acetonitrile)[Mn5O3(tert-butylphosphonate)2(PhCOO)5(1,10-phenanthroline)2]*H2O*(acetonitrile)

合成工艺路线路线简述

    📜氯代叔丁烷 反应生成 叔丁基磷酸
    参考文献:Murav'Ev,I.V.; Fedorovich,I.S.,Journal Of General Chemistry Of The Ussr,1975,Vol. 45,P. 1711-1713
    标题:Murav'Ev,I.V.; Fedorovich,I.S.,Journal Of General Chemistry Of The Ussr,1975,Vol. 45,P. 1711-1713

    专利信息


    专利号:US-12037636-B2
    优先权日:2018-07-19
    标题 :Polynucleotide synthesis method, kit and system
    发明人:MILTON JOHN; NAYYAR SOBIA; RIEDL JAN; OGAKI RYOSUKE
    权利人:OXFORD NANOPORE TECH PLC
    摘要:The invention relates to new methods for synthesising polynucleotide molecules according to a predefined nucleotide sequence. The invention also relates to methods for the assembly of synthetic polynucleotides following synthesis, as well as systems and kits for performing the synthesis and/or assembly methods.

    专利号:US-2017029451-A1
    优先权日:2013-12-05
    标 题:Branched chain acyclic nucleoside phosphonate esters and methods of synthesis and uses thereof
    发明人:WARE ROY W; DOWNEY AARON L; LANIER ERNEST RANDALL; SETHNA PHIROZE; SELLESETH DEAN
    权利人:CHIMERIX INC
    摘要:The present invention is directed to branched chain nucleoside phosphonate ester compounds and methods of synthesis thereof. The present invention is also directed to pharmaceutical compositions comprising branched chain nucleoside phosphonate ester compounds and methods of treating and/or preventing double stranded DNA viral infection and/or viral infection associated disease or disorder.

    专利号:US-9982006-B2
    优先权日:2014-08-21
    标题:2′-chloro aminopyrimidinone and pyrimidine dione nucleosides
    发明人:CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
    权利人:GILEAD SCIENCES INC
    摘要:Provided herein are formulations, methods and substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds.

    专利号:US-7511113-B2
    优先权日:2002-04-26
    标题:Oligomeric hydroxy arylether phthalonitiles and synthesis thereof
    发明人:KELLER TEDDY M; DOMINGUEZ DAWN D
    权利人:US NAVY
    摘要:An aromatic ether oligomer or polyaromatic ether comprising the formula:n n O—Ar n ;n nwherein Ar is an independently selected divalent aromatic radical; formed by reacting a dihydroxyaromatic with a dihaloaromatic; and wherein the reaction is performed in the presence of a copper compound and cesium carbonate. The polyaromatic ether is formed when neither the dihydroxyaromatic nor the dihaloaromatic is present in an excess amount. The aromatic ether oligomer is formed by using an excess of either dihydroxyaromatic or dihaloaromatic. A phthalonitrile monomer comprising the formula:n n nformed by reacting a 3- or 4-nitrophthalonitrile with a hydroxy-terminated aromatic ether oligomer. A thermoset formed by curing the phthalonitrile monomer. Processes for forming all the above.

    专利号:US-9828388-B2
    优先权日:2014-07-28
    标题:Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections
    发明人:CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
    权利人:GILEAD SCIENCES INC
    摘要:Provided herein are formulations, methods and substituted thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-d]pyrimidine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-d]pyrimidine compounds.

    专利号:US-9701682-B2
    优先权日:2013-11-11
    标题:Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections
    发明人:CLARKE MICHAEL O'NEIL HANRAHAN; DOERFFLER EDWARD; MACKMAN RICHARD L; SIEGEL DUSTIN
    权利人:GILEAD SCIENCES INC
    摘要:Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Dipankar Sahoo, Et Al. Di-, Tri- And Tetranuclear Molecular Vanadium Phosphonates: A Chloride Encapsulated Tetranuclear Bowl. Dalton Trans. 2014 Jul 28;43(28):10898-909.
    [参考文献]: Justus Tnnemann, Et Al. Borophosphonate Cages: Easily Accessible And Constitutionally Dynamic Heterocubane Scaffolds. Chemistry. 2012 Aug 6;18(32):9939-45.
    [参考文献]: Saskia Speed, Et Al. Hexanuclear Copper(Ii) Cages Built On A Central {μ3-O···h···μ3-O} Moiety, 1,3-Bis(Dimethylamino)-2-Propanolato And Capping R-Phosphonates: Crystal Structures, Magnetic Behavior, And Dft Studies. Inorg Chem. 2012 Jun 18;51(12):6842-50.
    [参考文献]: Vadapalli Chandrasekhar, Et Al. Multicomponent Assembly Of Anionic And Neutral Decanuclear Copper(Ii) Phosphonate Cages. Inorg Chem. 2012 May 21;51(10):5605-16.

    合成参考文献


    参考文献:10.1021/ac035072y
    摘要:Zhou Y, Yu B, Shiu E, Levon K. Potentiometric sensing of chemical warfare agents: surface imprinted polymer integrated with an indium tin oxide electrode. Anal Chem. 2004 May 15;76(10):2689–93. doi: 10.1021/ac035072y.
    参考文献:10.1021/ic701343s
    摘要:Wang M, Ma CB, Yuan DQ, Wang HS, Chen CN, Liu QT. Synthesis and characterization of a family of penta- and tetra-manganese(III) complexes derived from an assembly system containing tert-butylphosphonic acid. Inorg Chem. 2008 Jul 07;47(13):5580–90. doi: 10.1021/ic701343s.
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