CAS: 481-72-1; 1,8-Dihydroxy-3-(Hydroxymethyl)Anthracene-9,10-Dione

相似化合物

478-43-3 481-72-1 65175-75-9

上下游产品

CAS号481-74-3 大黄酚 | CAS号65615-58-9 (4,5-dihydroxy-... | CAS号72036-12-5 3-(bromomethyl)... | CAS号1415-73-2 芦荟苷 | CAS号72049-23-1 4-Bromo-3-carbo... | CAS号2161-90-2 1-甲氧基-1,3-环己二烯 | CAS号124010-11-3 ethyl 4-acetylo... | CAS号478-43-3 大黄酸 | CAS号481-74-3 大黄酚 | CAS号65615-58-9 (4,5-dihydroxy-... | CAS号613-12-7 2-甲基蒽 | CAS号102831-03-8 3-[[(2R,3R,4R,5... | CAS号25395-11-3 三乙酰芦荟大黄素(杂质A) | CAS号14963-97-4 3-甲氧基苯-1,2-二甲酸 | CAS号72049-14-0 1-hydroxy-3-(hy... | CAS号72049-24-2 4,5-dimethoxy-9... | CAS号75694-01-8 3-(chloromethyl...

大黄酚置于n-溴代丁二酰亚胺(Nbs),水,Calcium Carbonate,过氧化苯甲酰体系中,用 1,4-二氧六环,四氯化碳 作为反应溶剂,化学反应 13.0H,反应生成 芦荟大黄素
参考文献:Knipholone和相关抗疟原虫苯基蒽醌的对映体对映选择性全合成.
标题:Knipholone和相关抗疟原虫苯基蒽醌的对映体对映选择性全合成.
摘要:"内酯概念"已被有效地用于苯丙醚酮和相关的天然苯基蒽醌的第一次熵-对映选择性合成.除了对联芳基轴的区域和立体选择性构建之外,另一个重要步骤是通过合成的乙酰弗里德-克拉夫茨型乙酰化反应或通过首先在简化模型上测试的邻位选择性弗里斯重排"合成后期"引入c-乙酰基系统并随后应用于天然产品及其简化类似物的高度阻转选择性制备以进行生物测试.这些天然联芳基,其前体和非天然类似物的合成可用性使得人们对这些有趣的联芳基的抗血浆活性进行了更广泛的研究.
DOI:10.1021/jo020189S

专利信息

专利号:US-6531591-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:EP-1202998-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:US-10407401-B1
优先权日:2018-08-04
标题 :Process for synthesis of Oroxylin A
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA; SAMI LABS LTD
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalin is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A glucuronide methyl ester which on de-glycosylation results in the formation of Oroxylin A.

专利号:EP-1202998-A1
优先权日:1999-07-07
标题:Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

专利号:DE-60006680-T2
优先权日:1999-07-07
标题 :SYNTHESIS OF STABLE CHINONE- AND PHOTOREACTIVE KETONE-PHOSPHORAMIDITE REAGENT FOR SOLID-PHASE SYNTHESIS OF PHOTOREACTIVE OLIGOMER CONJUGATES

专利号:WO-0104129-A1
优先权日:1999-07-07
标题:Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates