专利号:US-7393980-B2 优先权日:2001-05-17 标题:Use of a composition of an ionic nature as a substrate reagent, a composition constituting a fluorination reagent and a method using same 发明人:GARAYT MAXIME; LE BOULAIRE VIRGINIE; GREE DANIELLE; GREE RENE; SCHANEN VINCENT; SPINDLER JEAN-FRANCIS 权利人:RHODIA CHIMIE SA 摘要:The invention relates to a novel method for producing nucleophilic substitutions, particularly of type SNAr and SN2. More specifically, the invention relates to the use as a fluorinating reaction medium of ionic liquid or fused salt comprising at least four carbon atoms. The invention can be used for the synthesis of fluoride derivatives.
专利号:US-2006167268-A1 优先权日:2002-04-09 标 题:Growth hormone secretagogues 发明人:EVERS BRITTA; GERD RUEHTER; MARTIN DE LA NAVA EVA M; TEBBE MARK J 权利人:ELI LILLY AND COMPANY PATENT D 摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.
专利号:US-7396846-B2 优先权日:2002-04-09 标题:Growth hormone secretagogues 发明人:EVERS BRITTA; GERD RUEHTER; MARTIN DE LA NAVA EVA MARIA; TEBBE MARK JOSEPH 权利人:LILLY CO ELI 摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.
专利号:US-10270034-B2 优先权日:2014-05-26 标题 :Tetra-aryl indacenodithiophene-based polycyclic polymers and their use 发明人:MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID 权利人:MERCK PATENT GMBH 摘要:The present invention relates to compounds comprising a tetra-aryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.
专利号:US-9914742-B2 优先权日:2014-07-29 标 题 :Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use 发明人:MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID 权利人:MERCK PATENT GMBH 摘要:The present invention relates compounds comprising a tetra-heteroaryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.
专利号:US-9502658-B2 优先权日:2013-04-22 标题 :Fullerene derivatives and related materials, methods, and devices 发明人:JACKSON EDWARD A; RICHTER HENNING; BLOUIN NICOLAS; BERNY STÉPHANE 权利人:NANO-C INC; MERCK PATENT GMBH 摘要:The invention relates to improved fullerene derivatives, to methods for their synthesis and any educts or intermediates used in such methods, to compositions and formulations containing fullerene derivatives, to the use of the fullerene derivatives, compositions and formulations in, or for the preparation of, organic electronic (OE) devices like for example organic photovoltaic (OPV) devices or organic photodetectors (OPD), and to OE, OPV and OPD devices comprising, or being prepared from, these fullerene derivatives, compositions or formulations.
参考文献:10.1016/j.bmc.2012.08.054 摘要:Negoro K, Yonetoku Y, Moritomo A, Hayakawa M, Iikubo K, Yoshida S, Takeuchi M, Ohta M. Synthesis and structure-activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists. Bioorg Med Chem. 2012 Nov 01;20(21):6442–51. doi: 10.1016/j.bmc.2012.08.054.