CAS: 14898-87-4; 1-Phenyl-2-Propanol

该化合物是属于酒精类的有机化合物.它具有一个手性中心,产生两种抗菌剂,具有不同的特性和反应力.这种复合物一般是无色的,可粉黄的液体,具有一种特殊的气味.它具有中度溶解,在水中更易溶解,有机溶剂中更易溶解,反映其非生殖性.该苯基组的存在有助于其缺水特性,而氢氧(-OH)组则增加其极性.(+/-)-苯基-2-丙醇经常用于有机合成,并用作生产药品和其他精美化学品的中间体.它的性能性质使其特别引起对非对称合成和液溶液过程的兴趣.此外,它可以参与各种化学反应,包括氧化和酯化,使其在合成有机化学中成为灵敏性化合物.在处理该物质时,应当采取安全防范措施,因为如果是吸入或吸入,可能会对健康造成危害.

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2-hydroxy-1-phenylpropylamine methyl magnesium iodide 2-iodo-1-phenylethan-1-ol 2-iodo-2-phenylethanol (+/-)-phthalic acid mono-(1-methyl-2-phenyl-ethyl ester) 1-phenylpropan-2-yl naphthalen-1-ylcarbamate 1-phenylpropan-2-yl chloroformate 2-Methyl-3-nitro-benzoic acid 1-methyl-2-phenyl-ethyl ester

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    专利信息


    专利号:WO-0140193-A1
    优先权日:1999-12-03
    标题:Method for the synthesis of pyrazolines
    发明人:BOLDI ARMEN M
    权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
    摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-6723798-B1
    优先权日:2000-08-28
    标 题:Resins having vinyl ether linker for the solid phase organic synthesis
    发明人:YOO SUNGEUN; GONG YOUNGDAE; SEO JINSOO
    权利人:KOREAN RES INST OF CHEMICAL TE
    摘要:The present invention relates to a resin having a vinyl ether linker and more particularly, to a resin having a vinyl ether linker expressed by formula (I), useful for the synthesis of compounds having hetero atoms such as alcohol, thiol, imidazole, triazole and tetrazole by employing combinatorial chemical synthesis on solid supports.

    专利号:US-7462738-B2
    优先权日:2006-05-24
    标题:Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof
    发明人:HEDVATI LILACH; GILBOA EYAL; AVHAR-MAYDAN SHARON
    权利人:TEVA PHARMA
    摘要:Provided are processes for the synthesis of R-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof, intermediates in the synthesis of S-pregabalin.

    专利号:US-11717498-B2
    优先权日:2013-12-31
    标题 :Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms
    发明人:POPP KARL; MECKLER HAROLD
    权利人:Chemapotheca LLC; PHARMAPOTHECA A INC
    摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

    专利号:US-6469193-B1
    优先权日:1999-02-26
    标 题 :Efficient synthesis of alkyl carbonates
    发明人:JUNG KYUNG WOON
    权利人:UNIV SOUTH FLORIDA
    摘要:Efficient synthetic methods towards mixed aliphatic carbonates through the three component couplings of aliphatic alcohols, alkyl halides and carbon dioxide in the presence of cesium carbonate and tetrabutylammonium iode (TBAI). Due to their enhanced nucleophilicities, cesium alkoxides are smoothly incorporated into CO 2 , allowing for mild reaction conditions such as ambient temperatures and short reaction durations. Various primary and secondary substrates are compatible under the standard conditions, offering high yields, while chiral templates such as α-hydroxy carbonyls are resistant to racemization.

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    合成参考文献


    摘要:Wicha, J., Science of Synthesis, (2009) 48, 169.
    摘要:Araki, S.; Hirashita, T., Science of Synthesis Knowledge Updates, (2010) 4, 165.
    摘要:Scammells, P. J., Science of Synthesis Knowledge Updates, (2013) 2, 445.
    摘要:De Wildeman, S.; Sereinig, N., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 166.
    摘要:Stoltz, B.; Ebner, D. C.; Park, N., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 218.
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