CAS: 140-40-9; N-(5-Nitrothiazol-2-yl)Acetamide

该化合物是一种杂环有机化合物,其特点是有硫诺环以及硝基和乙基氨基化合物,该化合物一般是黄色至橙色晶状固体,以其在制药和农用化学品中的潜在用途而著称.硫诺子环具有芳香特性,而硝基化合物组则增强了其反应性,使其在各种化学合成中有用.乙基环组增加了其在有机溶剂中的溶性,并能够影响其生物活动.该化合物经常被研究其抗微生物和抗硫基特性,反映其在药用化学中的重要性.此外,在标准条件下,该混合物的稳定性使它成为进一步化学修改的合适选择.安全数据表明,与许多硝基混合物一样,应对该化合物时应谨慎处理其潜在的毒性和环境关切.总体而言,2-(乙基米诺基)-5-硝基甲基甲酸盐是一种具有显著化学特性和应用的多种特性.

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CAS号121-66-4 2-氨基-5-硝基噻唑 | CAS号108-24-7 乙酸酐 | CAS号2719-23-5 2-乙酰胺基噻唑 | CAS号7336-54-1 2-乙酰氨基-5-溴-1,3-噻唑 | CAS号625-58-1 硝酸乙酯 | CAS号57530-25-3 thiazol-2-amine... | CAS号121-66-4 2-氨基-5-硝基噻唑

合成工艺路线路线简述

    📜2-乙酰胺基噻唑置于硝酸,乙酸酐体系中,化学反应生成醋胺硝唑
    参考文献:The Nitration Of 2-Nitraminothiazoles And 2-Acetamidothiazoles
    标题:The Nitration Of 2-Nitraminothiazoles And 2-Acetamidothiazoles
    摘要:通过使用99-100%硝酸和乙酸酐的混合物进行硝化反应,已经证明2-硝基氨基噻唑,例如2-硝基氨基-5-硝基噻唑和4-甲基-2-硝基氨基-5-硝基噻唑,可以以互变异构的硝基亚胺形式反应.硝化反应发生在噻唑环的三位.在噻唑环的二位具有乙酰胺基团的化合物,例如2-乙酰胺基-5-溴-2-噻唑和2-乙酰胺基-5-甲基噻唑,也可以在三位硝化,表明从乙酰胺基团到乙酰亚胺基团的互变异构.
    Doi:10.1139/v53-118

    海关参考信息

    专利信息


    专利号:US-11958866-B1
    优先权日:2023-04-07
    标题:Synthesis of thiazole derivatives
    发明人:NOOR AWAL; KHAN EZZAT; KHAN UMAR ALI
    权利人:UNIV KING FAISAL
    摘要:A synthetic protocol to use a thiourea or urea compound and auric chloride as starting materials to obtain thiazole and benzothiazole derivatives. The synthesis can be conducted at room temperature and the final compound can result from cyclization of the thiourea or urea compound in the presence of an Au salt from the auric chloride.

    专利号:US-2024286909-A1
    优先权日:2023-02-24
    标 题 :Production of hexachlorodisiloxane
    发明人:CHITTURI VENKATESWARA RAO; KOROLEV ANDREY
    权利人:WONIK MAT NORTH AMERICA LLC
    摘要:A method for the synthesis of perchlorodisiloxanes, and particularly hexachlorodisiloxane (Si2OCl6, HCDSO), using an amount of tetrachlorosilane (SiCl4) with an amount of molybdenum trioxide (MoO3). The method, in its broadest form, can be used to synthesize perchlorosiloxanes of the general formulae SixOx−1Cl2x+2. A catalytic amount of anhydrous HCl may be used to speed the reaction.

    专利号:US-11814399-B1
    优先权日:2023-04-07
    标 题 :Synthesis of thiazole derivatives

    专利号:CN-107722288-A
    优先权日:2017-10-18
    标题 :Synthesis of a Eu‑MOFs material and its application in antibiotic identification

    专利号:US-2022370984-A1
    优先权日:2021-05-21
    标 题:Polymeric sorbent fiber compositions incorporating metal organic frameworks
    发明人:WESTON SIMON C; KOROS WILLIAM J; Quan Wenying; LIVELY RYAN P; ZHANG FENGYI; ABNEY CARTER W; DEWITT STEPHEN J A; REALFF MATTHEW J; HOLMES HANNAH E; KAMATH MANJESHWAR G
    权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY; GEORGIA TECH RES INST
    摘要:Fiber compositions are provided that incorporate metal organic framework (MOF) materials into the polymeric matrix of the fiber. The metal organic framework materials can be incorporated by including MOF particles into a “dopeâ€? or synthesis solution used to form the fiber. The dope solution can then be used to form fibers that include 5.0 wt % or more of MOF in the resulting polymeric structural material of the fiber, relative to a weight of the fibers. In some aspects, the metal organic framework material can correspond to a MOF with selectivity for adsorption of CO 2 .

    专利号:CN-109400895-A
    优先权日:2018-10-19
    标 题 :A kind of rare earth terbium-based metal organic framework material, synthesis method and its application in antibiotic identification

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Layton HW, Simkins KL, Eggert RG. Efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs. Am J Vet Res. 1977 May;38(5):627-31. doi: 10.1038/nrrheum.2013.7. Epub 2013 Feb 19. Review.
    3: Goodhew EB, Secor WE. Drug library screening against metronidazole-sensitive and metronidazole-resistant Trichomonas vaginalis isolates. Sex Transm Infect. 2013 Sep;89(6):479-84. doi: 10.1136/sextrans-2013-051032. Epub 2013 Jun 22. Russian. Russian. Russian. Polish, Portuguese. French.
    13: HORTON-SMITH C, LONG PL. The effect of 2-amino-5-nitrothiazole, 2-acetylamino-5-nitrothiazole and furazolidone on the growth in vitro of Histomonas meleagridis. Ann Trop Med Parasitol. 1957 Mar;51(1):117-20.

    合成参考文献


    摘要:Antibiotics and Chemotherapy, 5(540), 1955
    参考文献:10.1007/bf00815548
    摘要:KIMMIG J, RIETH H. [Mycoses and trichomonads]. Arch Gynakol. 1961;195():31–43. doi: 10.1007/bf00815548.
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