CAS: 60410-16-4; (1R,4S)-4-Hydroxycyclopent-2-En-1-Yl Acetate

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相似化合物

54664-61-8 29783-26-4 60410-18-6

上下游产品

CAS号61305-31-5 acetic acid,4-(... | CAS号54664-61-8 Cis-3,5-二乙酰氧基-1-环戊烯 | CAS号60389-71-1 acetic acid,cyc... | CAS号108-05-4 乙酸乙烯酯 | CAS号29783-26-4 CIS-3,5-DIHYDRO... | CAS号98-00-0 糠醇 | CAS号59995-47-0 (4R)-(+)-羟基-2-环戊酮 | CAS号61305-37-1 4-(tetrahydro-p... | CAS号37517-41-2 (+/-)-cis-4-(2'... | CAS号87893-55-8 15-脱氧-Δ12,14-前列腺素J2 | CAS号81266-47-9 3-(硝甲基)环戊酮 | CAS号127129-72-0 3-(1-nitroethyl... | CAS号29783-26-4 CIS-3,5-DIHYDRO... | CAS号344751-82-2 (+/-)-3-(1'-nit... | CAS号34638-25-0 (1R,5S)-(+)-2-氧... | CAS号14320-37-7 3-环戊烯-1-酮 | CAS号155899-66-4 (3aR,4S,6R,6aS)... | CAS号158799-93-0 (1S,4R)-4-(6-ch... | CAS号104010-72-2 (+)-(3As,6as)-3...

合成工艺路线路线简述

    Cis-3,5-二乙酰氧基-1-环戊烯置于acetylcholinesterase体系中,用94%的收率获得产物(1S,4R)-顺式-4-乙酰氧基-2-环戊烯-1-醇
    参考文献:钯催化的分子内烯烃烯丙基化:双环系统的立体控制合成和烯丙基钯/烯烃顺式插入的证据
    标题:钯催化的分子内烯烃烯丙基化:双环系统的立体控制合成和烯丙基钯/烯烃顺式插入的证据
    摘要:的pd(o)催化的的环化(1-乙酰氧基-3-烯基)-2-环烯烃,和提供在高diastereo-双环系统(,)和对映聚体()纯度具有占优势的烯丙基钯/烯烃一致顺-插入.
    DOI:10.1016/s0040-4039(00)80586-9

    海关参考信息

    专利信息


    专利号:EP-2666771-A1
    优先权日:2012-05-24
    标题 :Synthesis of Aminocyclopentanetriol Derivatives
    发明人:STERK DAMJAN; CASAR ZDENKO
    权利人:LEK PHARMACEUTICALS
    摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor. nThe present invention provides in particular a process for the preparation of a compound of formula Vn ncomprising: na) providing a compound of formula IVn n, and nb) reducing the compound of formula IV with activated zinc in the presence of copper to give the compound of formula V.

    专利号:US-5144034-A
    优先权日:1990-04-06
    标题 :Process for the synthesis of cyclopentene derivatives of purines
    发明人:JOHNSON M ROSS; PEEL MICHAEL R; STERNBACH DANIEL D
    权利人:GLAXO INC
    摘要:This invention relates to a new process for preparing certain optically active cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1'R-cis isomer of carbovir, (1'R-cis)-2-amino-1,9-dihydro-9[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H-purin-6-one, an antiviral agent.

    专利号:US-5126452-A
    优先权日:1990-04-06
    标 题 :Synthesis of purine substituted cyclopentene derivatives
    发明人:VINCE ROBERT; PETERSON MARK L; LACKEY JOHN W; MOOK JR ROBERT A; PARTRIDGE JOHN J
    权利人:GLAXO INC
    摘要:This invention relates to new process for preparing certain optically active purine substituted cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1R-cis isomer of carbovir, (1R-cis)-amino-1,9-dihydro-9-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H-purin-6-one, an antiviral agent, and certain intermediates.

    专利号:US-2023174477-A1
    优先权日:2021-12-03
    标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester
    发明人:DAI MINGJI; SIMS HUNTER
    权利人:PURDUE RESEARCH FOUNDATION
    摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.

    专利号:US-5057630-A
    优先权日:1990-04-06
    标 题 :Synthesis of cyclopentene derivatives
    发明人:LACKEY JOHN W; MOOK JR ROBERT A; PARTRIDGE JOHN J
    权利人:GLAXO INC
    摘要:This invention relates to a new process for preparing certain optically active purine substituted cyclopentene derivatives including the antiviral agent, carbovir, and novel intermediates used in this process. In particular, this invention concerns a synthesis of (1R-cis)-4-hydroxymethyl-2-cyclopenten-1-ol, an intermediate in this process.

    专利号:US-2014378538-A1
    优先权日:2011-12-14
    标 题:Methods of responding to a biothreat
    发明人:BANCEL STEPHANE
    权利人:MODERMA THERAPEUTICS INC
    摘要:The present disclosure provides for devices, in particular mobile devices, which may be used in the synthesis of modified nucleic acid molecules, in particular modified mRNA molecules. The device for making the modified nucleosides, modified nucleotides and modified nucleic acids (e.g., mRNA) disclosed herein may be mobile devices comprising at least one sample block for insertion of one or more sample vessels, a device base with electronic control units for the sample block, a voltage supply, and one or more reagent(s) for the synthesis of at least one nucleic acid.
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    合成参考文献


    摘要:Cherkinsky, M.; Levinger, S., Science of Synthesis, (2010) 47, 482.
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