CAS: 59-47-2; 3-(O-Tolyloxy)Propane-1,2-Diol

上下游产品

CAS号95-48-7 邻甲酚 | CAS号96-24-2 3-氯-1,2-丙二醇 | CAS号556-52-5 缩水甘油 | CAS号56-81-5 甘油 | CAS号4549-72-8 sodium,2-methyl... | CAS号63991-86-6 3-(o-Tolyloxy)-... | CAS号25772-91-2 1-chloro-3-(2-m... | CAS号2210-79-9 2-甲苯缩水甘油醚 | CAS号106-89-8 环氧氯丙烷 | CAS号101693-39-4 (2R)-2-[(2-METH... | CAS号6055-48-7 托洛氯醇 | CAS号6288-77-3 [2-hydroxy-3-(2... | CAS号6288-82-0 2-methyl-4-[(2-... | CAS号533-06-2 1,2-Propanediol...

📜3-(邻甲苯氧基)-1,2-丙烷二醇二乙酸酯置于sodium Hydroxide体系中,用 异丙醇 作为反应溶剂,以20 Mg的收率获得产物甲酚甘油醚
参考文献:[14C]-标记的脂肪族和芳香族醇缩水甘油醚和甘油醚的合成
标题:[14C]-标记的脂肪族和芳香族醇缩水甘油醚和甘油醚的合成
摘要:[14C]-标记的缩水甘油醚和相应的甘油醚的合成描述了单官能化合物 1-十二醇和邻甲酚和双官能化合物 4,4'-二羟基-3,3',5,5'-四甲基联苯和 1,6-己二醇.该合成基于醇与 [u-14C]-表氯醇 (1) 之间的反应.使用氢氧化钠将芳香族化合物转化为相应的缩水甘油醚,使用氯化锡 (Iv) 作为催化剂将脂肪族化合物转化为相应的缩水甘油醚.因此,放射性标记的缩水甘油醚的产率在 50-80% 之间,化学纯度 >92%,放射化学纯度 >95%.缩水甘油醚的比活性对于单官能化合物约为 0.2 Mci/mmol,对于双官能化合物约为 0.4 Mci/mmol.
DOI:10.1002/(Sici)1099-1344(200002)43:2<147::Aid-Jlcr301>3.0.Co;2-H

专利信息

专利号:WO-2013171755-A2
优先权日:2012-03-09
标题:'combustion synthesis of nanocrystalline alkali and alkaline earth metal oxides or mixture thereof and its applications in synthesis of [4- (alkyl/aryl)-oxy- 1,3 -dioxolane-2- one] and 2-oxazolidinones'

专利号:US-4165330-A
优先权日:1972-07-31
标题 :Asymmetric synthesis via optically active chelating agents
发明人：WHITNEY THOMAS A; LANGER JR ARTHUR W
权利人:EXXON RESEARCH ENGINEERING CO
摘要:An asymmetric synthesis process which involves addition of optically active chelated organometal compounds of lithium, sodium, beryllium, magnesium, zinc, copper and cadmium to prochiral unsaturated substrates. The optically active chelating agent is not consumed and can be recycled.

专利号:US-7300639-B2
优先权日:2002-12-03
标 题:Process for removing metals from liquids
发明人：LIU WANSHENG
权利人:BRISTOL MYERS SQUIBB CO
摘要:A process is provided for removing one or more metals from liquids. Also provided is a process for the synthesis of aP2 inhibiting compounds having the formula (I) n nwherein R 1 , R 2 , R 3 , R 4 , HET, and X-Z are as described herein, which process comprising the step of removing one or more metals from a solution of the compound of formula I or an intermediate or precursor thereof. The processes for removing metal comprise the step of contacting the liquid with a solid extractant comprising a metal-binding functionality.

专利号:US-2005038301-A1
优先权日:2001-11-08
标题 :Chemical synthesis
发明人：KAVTARADZE LEVAN KITA; MANLEY-HARRIS MERILYN
摘要:The present invention relates to a method of producing vicinal diols from a compound, the method characterised by the step of reacting the compound with a moderately strong acid in the presence one or more reagents capable of supplying hydroxyl groups wherein the moderately strong acid is a strongly reducing agent, but has a conjugate base that is a weak nucleophile. In preferred embodiments the moderately strong acid is hypophosphorous acid and the reagent(s) capable of supplying hydroxyl groups is 2-propanol in water, where 2-propanol is water soluable and organic. This method is particularly applicable to the production of vicinal diols of steroids, including lanosterol. Once vicinal diols of lanosterol diols are formed they are then capable of being further reacted to produce high purity lanosterol.

专利号:US-6093805-A
优先权日:1991-01-22
标 题:Glycoside compounds and methods of synthesis
发明人：SHULL BRIAN K; TUINMAN ROELAND J; HOUSTON TODD A; KLEMKE R ERICH; KOREEDA MASATO
权利人:UNIV MICHIGAN
摘要:Novel glycosides, especially steroidal and non-steroidal glycosides are provided. The steroidal and non-steroidal glycosides preferably are prepared from aglycons which possess valuable properties such as pharmacological properties. The glycosides are prepared from useful aglycons and possess useful properties which are the same as those of their respective unglycosylated aglycons. The glycosides are provided in acylated and deacylated form. The acylated glycosides after hydrolysis of the acyl groups possess enhanced water solubility properties, as illustrated in the case where the aglycon is acetominophen.

专利号:ES-2965777-T3
优先权日:2012-05-16
标 题:Enzymatic synthesis of L-nucleic acids